左旋多巴联合物理疗法治疗弱视患儿的疗效及对图形视觉诱发电位的影响  

Efficacy of levodopa and physical therapy on children with amblyopia and its effect on pattern visual evoked potential

作　　者：乔瑛[1] 郅瑛 张婷[1] 赵隽 QIAO Ying;ZHI Ying＊;ZHANG Ting;ZHAO Jun(Ophthalmology Department,Xi＇an No.1 Hospital,Xi＇an 710002,China)

机构地区：[1]西安市第一医院眼科,陕西西安710002

出　　处：《临床医学研究与实践》2018年第22期77-78,共2页Clinical Research and Practice

摘　　要：目的观察左旋多巴联合物理疗法治疗弱视患儿疗效及对图形视觉诱发电位(P-VEP)的影响。方法选取我院2016年3月至2017年6月收治的弱视患儿54例,随机将其分为对照组和观察组,各27例。对照组接受物理疗法,观察组在此基础上口服左旋多巴片治疗,均连续治疗6个月。比较两组临床疗效、P-VEP及不良反应发生情况。结果观察组的治疗总有效率显著高于对照组(P<0.05);治疗后,两组P100潜伏期均缩短,P100波幅均增大,且观察组优于对照组(P<0.05);两组不良反应总发生率无显著差异(P>0.05)。结论左旋多巴辅以物理疗法治疗弱视患儿疗效显著,可有效改善P-VEP,且安全可靠,值得临床推广。Objective To observe the efficacy of levodopa and physical therapy in children with amblyopia and its effecton pattern visual evoked potential （P-VEP）. Methods Fifty-four children with amblyopia who admitted in our hospital fromMarch 2016 to June 2017 were randomly divided into control group and observation group, with 27 cases in each group.The control group received physical therapy, the observation group was treated with levodopa tablets orally on this basis,and they were treated continuously for 6 months. The clinical efficacy, P-VEP and incidences of adverse reactions werecompared between the two groups. Results The total effective rate of treatment in the observation group was significantlyhigher than that in the control group （P〈0.05）. After treatment, the latency of P100 shortened and the amplitude of P100increased in both groups, and those in the observation group were superior to the control group （P〈0.05）. There was nosignificant difference in the total incidences of adverse reactions between the two groups（P〉0.05）. Conclusion The efficacyof levodopa and physical therapy in the treatment of children with amblyopia is significant, and it can effectively improvethe P-VEP, it is safe and reliable, and worthy of clinical promotion.

关 键 词：左旋多巴 物理疗法 弱视患儿 

分 类 号：R777.44[医药卫生—眼科]