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作 者:殷志强 YIN Zhi-qiang(Department of Anesthesiology,Jinjiang grand hospital,Chengdu,Sichuan Sichuan Chengdu 610000)
机构地区:[1]四川省成都市锦江大观医院麻醉科,四川成都610000
出 处:《临床医药文献电子杂志》2018年第38期134-135,共2页Electronic Journal of Clinical Medical Literature
摘 要:目的研究七氟醚吸入麻醉对胃癌患者围术期血浆细胞因子的临床效果。方法选取我院2016年6月至2017年6月所收治的胃癌患者80例,根据患者入院时间分为实验组和对照组,每组各40例,对照组患者给予氯胺酮和芬太尼吸入麻醉,实验组患者给予七氟醚和芬太尼吸入麻醉,比较2组患者围术期手术情况以及血浆细胞因子的变化情况。结果对照组患者麻醉后1小时、麻醉后2小时血浆细胞因子指标高于实验组,数据对比差异性显著(P<0.05),手术结束后,2组对比无统计学意义(P>0.05)。结论七氟醚吸入麻醉对胃癌手术患者围术期间能够起到有效的控制作用,对患者血浆细胞因子变化情况起到制约作用,有效防治患者术后免疫功能受损以及避免患者术后发炎,值得在临床推广运用。Objective:To discuss the clinical effect of using sevoflurane inhalation anesthesia to gastric carcinoma on cytokines in perioperative period. Methods:Choosed 80 gastric carcinoma patients from Jun. 2016 to Jun. 2017 to divide into study group and controlled group with 40 cases in each. The controlled group were treated with ketamine and fentanyl inhalation anesthesia, the study group were treated with sevoflurane and fentanyl. Compared the cytokines of these two groups. Results:The index of cytokines after anesthesia 1 hour and 2 hours of controlled group were higher than study group, but no difference after operation(P〈0.05). Conclusion:Using sevoflurane inhalation anesthesia to gastric carcinoma on cytokines in perioperative period can restrain cytokines to prevent postoperative immune function of patients and to avoid postoperative inflammation to extend in clinic.
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