欧洲甲状腺协会成人甲状腺结节超声恶性危险分层指南临床应用价值  

The study of clinical values of european thyroid association guidelines for ultrasound malignancy risk stratification of thyroid nodules in adults

作　　者：张梦菲 卢川[1,2] 唐守信[1,2] 司云鹏 张家君[2] 薛爱喜 ZHANG Mengfei;LU Chuan;TANG Shouxin;SI Yunpeng;ZHANG Jiajun;XUE Aixi(School of Radiology,Taishan Medical University,Taian 271016,P.R.China;Department of Ultrasound,The Affiliated Hospital of Taishan Medical University,Taian 271000,P.R.China)

机构地区：[1]泰山医学院放射学院,山东泰安271016 [2]泰山医学院附属医院超声科,山东泰安271000

出　　处：《医学影像学杂志》2018年第7期1090-1092,1097,共4页Journal of Medical Imaging

摘　　要：目的探讨2017年欧洲甲状腺协会成人甲状腺结节超声恶性危险分层指南(EU-TIRADS)的临床应用价值。方法回顾性分析301例甲状腺结节患者446个结节的超声图像,根据EU-TIRADS对其分类并与术后病理结果对照,绘制ROC曲线,计算其敏感性、特异性、阳性预测值、阴性预测值,准确性。结果 446个甲状腺结节术后病理诊断:良性结节325个(72.9%),恶性结节121个(27.1%)。取EU-TIRADS 5时为阳性、其余分类诊断为阴性时,EU-TIRADS诊断甲状腺结节的曲线下面积最大(0.906),此时敏感性、特异性、阳性预测值、阴性预测值、准确性分别为95.9%、83.7%、68.6%、98.2%、87.0%。结论 EU-TIRADS能较准确地评估甲状腺结节的恶性风险,为临床诊疗提供指导依据。Objective The purpose of this study was to explore the clinical value of European Thyroid Association guidelines for ultrasound malignancy risk stratification of thyroid nodules in adults （the EU-TIRADS）. Methods Ultrasound images of 446 thyroid nodules in 301 patients who were confirmed by pathology were classified according to the EU-TIRADS. ROC curves were constructed to calculate the sensitivity, specificity, positive/negative predictive values and accruacy of EU-TIRADS. Results Of the 446 nodules, 325 nodules were benign and 121 nodules were malignant. Best cut-off point for diagnosing malignant by the EU-TIRADS were EU-TIRADS 5. The areas of curve, sensitivity, specificity, positive/negative predictive values and accuracy of EU-TIRADS were 0.906%, 95.9%, 83.7%, 68.6%, 98.2%, 87.0% at that point. Conclusion The EU-TIRADS may provide an appropriate method for estimating risk of malignancy for clinical management of thyroid nodules.

关 键 词：甲状腺结节 甲状腺影像与数据报告系统 欧洲甲状腺学会 超声 

分 类 号：R736.1[医药卫生—肿瘤] R455.1[医药卫生—临床医学]