口服氨基葡萄糖和布洛芬治疗颞下颌关节骨关节病的效果比较  

Comparison of Clinical Outcome Between Oral Glucosamine and Ibuprofen for Osteoarthrosis of Temporomandibular Joint

作　　者：吴燕丽[1] 魏明波[2] Wu Yanli;Wei Mingbo(Department of Pharmacy,Zhongnan Hospital of Wuhan University,Wuhan 430071,China;Department of Stomatology,Zhongnan Hospital of Wuhan University,Wuhan 430071,China)

机构地区：[1]武汉大学中南医院药学部,湖北武汉430071 [2]武汉大学中南医院口腔科,湖北武汉430071

出　　处：《医学新知》2018年第3期290-292,共3页New Medicine

摘　　要：目的探讨口服氨基葡萄糖治疗颞下颌关节骨关节病的临床效果。方法选取我院口腔科门诊42例颞下颌关节骨关节病且不愿行关节腔注射的患者，随机分为治疗组和对照组，各21例，治疗组口服氨基葡萄糖胶囊，对照组则口服布洛芬缓释胶囊。所有患者治疗前及治疗后进行Fricton颞下颌关节紊乱指数、最大开口度和疼痛指数评分。结果经治疗后42例患者的颞下颌关节紊乱指数、最大开口度和疼痛指数均得到改善，治疗组优于对照组。结论口服氨基葡萄糖治疗颞下颌关节骨关节病具有缓解临床症状，改善关节功能的作用。Objective To evaluate the short - term clinical effect of oral glucosamine and Ibuprofen for osteoar- throsis of temporomandibular joint. Methods 42 cases diagnosed as Osteoarthrosis of temporomandibular joint were collected and divided into two groups of 21 randomly. Treatment group received oral glucosamine, control group was treated with oral ibuprofen. Before and after treatment, Fricton＇s Index（ DI）, Maximum Mouth Opening Degree （MMO） and Pain Index（VAS） were analyzed and used to assess the clinical results. Results The Fricton＇s Indexes （DI）, Maximum Mouth Opening Degrees（MMO） and Pain Index（VAS） of all cases were improved after treatment, the clinical effects of treatment group were better than those of the control group. Conclusion Oral glucosamine can alleviate symptom and improve function for osteoarthrosis of temporomandibular joint.

关 键 词：颞下颌关节 骨关节病 氨基葡萄糖 布洛芬 

分 类 号：R782.6[医药卫生—口腔医学]