经尿道钬激光解剖性剜除术治疗表浅性膀胱肿瘤的临床疗效  

Clinical efficacy of transurethral holmium laser anatomical enucleation in the treatment of non muscle invasive bladder cancer

作　　者：张金刚 周健 马国忠 ZHANG Jingang;ZHOU Jian;MA Guozhong(Department of Urology,Heze Mudan People＇s Hospital,Heze 274015,China)

机构地区：[1]山东省菏泽市牡丹人民医院泌尿外科,山东菏泽274015

出　　处：《中国现代医生》2018年第19期51-53,F0003,共4页China Modern Doctor

摘　　要：目的总结并探讨经尿道钬激光解剖性剜除术治疗表浅性膀胱肿瘤(non muscle invasive bladder cancer,NMIBC)的临床疗效及安全性。方法回顾性分析我院2016年1月以来33例表浅性膀胱肿瘤患者,均选择行经尿道钬激光解剖性剜除术。治疗前膀胱镜活检病理均诊断为膀胱移行细胞癌。术后规律给予膀胱灌注1年,定期复查。结果 33例患者均手术顺利,术中无严重出血、闭孔神经反射、膀胱穿孔等并发症。术后随访平均16个月,3例肿瘤异位复发,未见原位复发,另1例出现肿瘤浸润进展及脑部转移。结论经尿道钬激光剜除术治疗表浅性膀胱肿瘤,操作简单,手术效果较好,解剖清晰,损伤小,复发率低,是一种安全有效的方法。Objective To summarize and explore the clinical efficacy and safety of transurethral holmium laser anatom- ical debridement for the treatment of non muscle invasive bladder cancer. Methods 33 patients with superficial bladder cancer since January 2016 in this hospital were retrospectively analyzed. The patients were treated with transurethral holmium laser anatomical enucleation. The cystoscopic biopsy pathology before treatment was diagnosed as bladder transitional cell carcinoma. Postoperatively, the bladder perfusion was performed for 1 year regularly and the patients were reviewed regularly. Results 33 patients were operated smoothly.No serious complications such as severe hemor- rhage, obturator nerve reflex, and bladder perforation occurred during the surgery. After an average of 16 months of fol- low-up, 3 cases of tumor had ectopic recurrence, and no original recurrence was observed. Another case had tumor in- filtration progression and brain metastasis. Conclusion Transurethral holmium laser anatomical enucleation is safe and effective in the treatment of non muscle invasive bladder cancer with simple operation, good surgical results, clear anatomy, less damage, and low recurrence rate.

关 键 词：膀胱肿瘤 表浅性 钬激光 解剖性 

分 类 号：R737.14[医药卫生—肿瘤]