射频消融联合经皮椎体成形术治疗脊柱转移瘤  

Effects of radiofrequency ablation combined with percutaneous vertebroplasty on spinal metastases

作　　者：王林杰[1] 孙国绍[1] 吴青坡[1] 王林飞 盛伟超 高延征[3] Wang Linfie;Sun Guoshao;Wu Qingpo;Wang Linfei;Sheng Weichao;Gao Yanzheng(Department of First Orthopedics,the First People＇s Hospital of Pingdingshan,Pingdingshan 467099,Chin;Department of Orthopedics,Pingmei Shenma Medical Group General Hospital,Pingdingshan 467099,Chin;Department of Orthopedics,Henan Provincial People＇s Hospital,Zhengzhou 450003,China)

机构地区：[1]河南省平顶山市第一人民医院骨一科,467099 [2]平煤神马医疗集团总医院骨科,河南平顶山467099 [3]河南省人民医院骨科,郑州450003

出　　处：《中国实用医刊》2018年第13期23-25,共3页Chinese Journal of Practical Medicine

基　　金：河南省科技创新杰出人才计划项目（154200510028）

摘　　要：目的分析射频消融联合经皮椎体成形术治疗脊柱转移瘤的临床疗效，并探讨其应用价值。方法选取平顶山市第一人民医院2015年5月至2016年5月收治的70例脊柱转移瘤患者作为研究对象，将其随机分为对照组与观察组，每组35例。对照组采用单纯经皮椎体成形术进行治疗，观察组采用射频消融联合经皮椎体成形术方案进行治疗，比较两组治疗前后的疼痛视觉模拟评分（VAS）、骨水泥外渗率及肿瘤复发率。结果两组治疗后近期VAS评分均低于治疗前，差异有统计学意义（P〈0．05）；治疗后观察组近期VAS评分低于对照组，但差异未见统计学意义（P〉0．05）；观察组骨水泥外渗率及肿瘤复发率均低于对照组，差异有统计学意义（P〈0．05）。结论射频消融联合经皮椎体成形术和单纯使用经皮椎体成形术均能有效改善脊柱转移瘤患者的疼痛状况，但前者骨水泥外渗率及肿瘤复发率均更低，患者获益更大。Objective To evaluate the clinical efficacy of radiofrequency ablation combined with percutaneous vertebroplasty on spinal metastases and to investigate its application value. Methods Sev- enty patients with spinal metastases who were hospitalized in the First People＇s Hospital of Pingdingshan from May 2015 to May 2016 were selected as research objects and were randomly divided into control group and observation group, with 35 cases in each group. Patients in control group were treated by sim- ple percutaneous vertebroplasty. Patients in observation group were treated by radiofrequency ablation combined with percutaneous vertebroplasty. The pain visual analogue scale （VAS） score, leakage rate of bone cement and tumor recurrence rate before and after treatment were compared between the two groups. Results The VAS scores of the two groups after treatment were significantly lower than those before treatment （ all P 〈 0. 05 ）. The VAS score of observation group was lower than that of control group after treatment, but the difference was not statistically significant （ P 〉 0. 05 ） ; leakage rate of bone cement and tumor recurrence rate of observation group were significantly lower than those of control group, the difference was statistically significant （P 〈 0.05 ）. Conclusions In the clinical treatment of spinal me- tastases, radiofrequency ablation combined with pereutaneous vertebroplasty and only use percutaneous vertebroplasty both can effectively alleviate the patient＇s pain, but the former has lower bone cement ex- travasation rate and lower tumor recurrence rate, by which patients are benefited more.

关 键 词：脊柱转移肿瘤 射频消融 经皮椎体成形术 疗效分析 

分 类 号：R738.1[医药卫生—肿瘤]