性腺外生殖细胞肿瘤的诊治现状和进展  

Updates and progress in clinical diagnosis and treatment of extragonadal germ cell tumors

作　　者：樊继全 周红霞 刘辛秀 昌喻 李贵玲[1] Fan Jiquan;Zhou Hongxia;Liu Xinxiu;Chang Yu;Li Guiling(Union Hospital,Tongfi Medical College of Huazhong University of Scienee and Technology,Hubei Wuhan 430022,China)

机构地区：[1]华中科技大学同济医学院附属协和医院,湖北武汉430022

出　　处：《现代肿瘤医学》2018年第13期2138-2141,共4页Journal of Modern Oncology

摘　　要：性腺外生殖细胞肿瘤约占所有生殖细胞肿瘤的2%～5%,好发于人体中线部位,尤其多见于纵膈、腹膜后区及松果体等部位,其中纵膈生殖细胞肿瘤占所有性腺外生殖细胞肿瘤的50%～70%。由于该肿瘤临床表现、组织类型、发病部位的多样性,其诊断、治疗策略及预后不同于与生殖腺原发生殖细胞肿瘤,因此,本文将综述性腺外生殖细胞肿瘤的临床表现、诊断、治疗及预后相关因素,以期为临床治疗与研究提供参考。Extragonadal germ cell tumors represent up to 2% -5% of all germ cell tumors. They are mainly local- ized along the median axis, especially in the mediastinmm, retroperitoneum, and pineal gland ,while the primary medi- astinal germ cell tumors accounts for 50% - 70% of all these malignancies. Due to the complicated clinical manifesta- tions, histological types and primary sites, there are great differences between the diagnosis, treatment strategies and prognosis from those of primary gonadal glands. Therefore, we reviewed the updates and progress in the clinical mani- festations,diagnosis,treatment and prognostic factors of extragonadal germ cell tumors, as to offer some references for further clinical treatment and research.

关 键 词：性腺外生殖细胞肿瘤 精原细胞瘤 非精原细胞瘤 

分 类 号：R736.8[医药卫生—肿瘤]