特定电磁波联合低分子量肝素钙预防PICC血栓的临床研究  

Effect of TDP plus low-molecular-weight heparins calcium on prevention of venous thrombosis caused by PICC

作　　者：兰海燕[1] 冯国生[1] 蒿艳蓉[1] 袁贤彬[1] 谢嫣嫣[1] 易中秋 曹宇华[1] LAN Hai-yan;FENG Guo-sheng;HAO Yan-rong(The First Department of Chemotherapy,the People＇s Hospital of Guangxi Zhuang Automonous Region,Nanning 530021,China)

机构地区：[1]广西壮族自治区人民医院化疗一区,南宁530021

出　　处：《中国临床新医学》2018年第6期541-543,共3页CHINESE JOURNAL OF NEW CLINICAL MEDICINE

基　　金：广西卫计委科研课题(编号:Z2015354)

摘　　要：目的观察特定电磁波(TDP)联合低分子量肝素钙预防恶性肿瘤患者经外周置入中心静脉导管(PICC)后发生静脉血栓的效果。方法将503例留置PICC的恶性肿瘤患者随机分为观察组249例和对照组254例。观察组给予皮下注射低分子量肝素钙联合TDP照射,对照组仅给予低分子量肝素钙皮下注射,比较两组患者静脉血栓的发生率。结果观察组静脉血栓发生率7.23%,较对照组13.78%明显下降,差异有统计学意义(P=0.017)。结论患者在PICC置管后给予TDP联合低分子肝素钙可明显降低静脉血栓发生率。Objective To explore the effect of special electromagnetic wave（ Te-ding Dian-ci-bo Pu,TDP）plus low-molecular-weight heparins calcium on preventing venous thrombosis in the patients with malignant tumors after peripherally inserted central catheter（ PICC）. Methods 503 patients with malignant tumors who received PICC were randomly divided into the observation group（ n = 249） and the control group（ n = 254）. The observation group was treated with subcutaneous injection of low-molecular-weight heparins calcium plus TDP. The control group was treated with low-molecular-weight heparins calcium. The incidence of venous thrombosis was compared between the two groups. Results The incidence of venous thrombosis in the observation group（ 7. 23%） was significantly lower than that in the control group（ 13. 78%）（ P = 0. 017）. Conclusion TDP plus low-molecular-weight heparins calcium can reduce the incidence of venous thrombosis in the patients with malignant tumors after PICC.

关 键 词：特定电磁波 低分子量肝素钙 经外周置入中心静脉导管 静脉血栓 

分 类 号：R73[医药卫生—肿瘤] R47[医药卫生—临床医学]