个体化固定在鼻咽癌调强放疗中的应用研究  

Application study of individual immobilization to intensity modulated radiotherapy of nasopharyngeal carcinoma

作　　者：李陆军[1] 李志聪[1] 谢金莲[1] 余海坤[1] 高健全[1] Li Lujun;Li Zhicong;Xie Jinlian;Yu Haikun;Gao Jianquan(Department of Radiation Oncology,Wuzhou Red Cross Hospital,Guangxi Wuzhou 543000,China)

机构地区：[1]梧州市红十字会医院放疗科,广西梧州543000

出　　处：《现代肿瘤医学》2018年第14期2278-2281,共4页Journal of Modern Oncology

摘　　要：目的:探讨个体化固定在鼻咽癌(MPC)调强放疗(IMRT)中的应用。方法:选取2014年3月至2016年6月在本院放疗科接受IMRT的100例鼻咽癌患者。A组51例采用头颈肩热塑膜+标准头枕固定,B组49例采用头颈肩热塑膜+真空垫+口腔支架固定。在患者的治疗过程中每周均用电子射野影像系统拍摄正位和侧位的等中心验证图像一次,整个疗程拍摄六次。A、B两组组间摆位误差比较采用独立样本t检验,B组内第二至六周分别与第一周比较采用配对样本t检验。P<0.05为差异有统计学意义。结果:组间摆位误差对比结果B组在腹背方向和头脚方向上的摆位误差优于A组。第二至第六周的摆位误差分别和第一周的比较结果 B组患者有很高的摆位重复性。结论:头颈肩热塑膜+真空垫+口腔支架的固定方式更有利于提高鼻咽癌调强放疗的摆位精度和重复性,值得推荐临床使用。Objective： To explore the application of individual immobilization to intensity-modulated radiotherapy of nasopharyngeal carcinoma. Methods： 100 nasopharyngeal carcinoma patients who underwent IMRT from March 2014 to June 2016 in our hospital were selected. Group A of 51 patients with head and neck shoulder mask ＋ pillow,Group B of 49 patients with head and neck shoulder mask ＋ vacuum pad ＋ precise bite. In the course of the treatment of patients with EPID every week to shoot the verification film of the anteroposterior and lateral,the entire course of six. Paired t test was used to evaluate the differences. Results： The setup error in group B was better than group A in the direction of dorsoventrally and cranial-caudal. Group B patients had a high placement repeatability. Conclusion：The head and neck shoulder mask ＋ vacuum pad ＋ precise bite immobilization technique are more accurate and repeatability when compared to the head and neck shoulder mask ＋ pillow fixation method,worthy of recommendation for clinical use.

关 键 词：鼻咽癌 调强放疗 摆位误差 

分 类 号：R739.6[医药卫生—肿瘤]