支气管镜联合液基细胞学在肺癌诊断的应用  

Application of Bronchoscopy Combined with Liquid Cytology in Diagnosis of Lung Cancer

作　　者：林桂阳[1] 郑冠英[1] 江淑平 LIN Guiyang,ZHENG Guanying,JIANG Shuping(Fujian Provincial Hospital, Fuzhou 350001, Chin)

机构地区：[1]福建省立医院,福建福州350001

出　　处：《中外医学研究》2018年第16期53-55,共3页CHINESE AND FOREIGN MEDICAL RESEARCH

摘　　要：目的:探讨液基细胞学检测技术(liquid-based cytology test,LCT)与支气管镜联合检查在肺癌诊断中的临床应用价值。方法:支气管镜检查联合LCT细胞病理诊断笔者所在医院2017年1-12月收集的肺癌患者131例,与2016年使用传统的直接涂片技术作细胞病理诊断的肺癌患者97例作为对比,进行分型比较,计算检出率。结果:在联合使用LCT技术组,细胞病理报告阳性率为82.4%(108/131),高于传统涂片组的54.6%(53/97),其中中央型肺癌阳性率为90.3%(93/103),高于传统涂片组的56.4%(44/78),差异均有统计学意义(P<0.01)。另有31.5%的LCT细胞病理诊断可直接区分肿瘤的病理分型,高于传统涂片组的9.4%。结论:LCT技术支气管镜检查联合应用可以提高肺癌的诊断阳性率,尤其在中央型肺癌的诊断更具优势,且对肿瘤的分型的判断具有辅助意义。Objective：To explore the clinical application value of liquid-based cytology test combined with bronchoscopy in the diagnosis of lung cancer.Method：A total of 131 lung cancer patients were examined by bronchoscopy with LCT in January-December 2017,compared with 97 cases of lung cancer diagnosed by direct smear in 2016.The detection rate was calculated and compared.Result：In the combined LCT group,the positive rate of cytopathological reports was 82.4 %（108/131）,higher than the 54.6%（53/97） of the traditional smear group,the difference was statistically significant（P〈0.05）.The positive rate of central lung cancer was 90.3%（93/103）, which was higher than that of the traditional smear group（56.4%）（44/78）,the difference was statistically significant（P〈0.05）.Conclusion：LCT combined with bronchoscopy can improve the positive rate of lung cancer diagnosis,especially it has more advantageous for the diagnosis of central lung cancer,besides,it is helpful to judge the pathological type.

关 键 词：液基细胞学检测技术 支气管镜检查 肺癌诊断 

分 类 号：R734.2[医药卫生—肿瘤]