长链非编码RNAs在口腔鳞癌中的研究进展  

Research progress of Long non-coding RNAs in oral squamous cell carcinoma

作　　者：徐文品 焦琨 张伟[1] XU Wenpin;JIAO Kun;ZHANG Wei(Department of Oral and Maxillofacial Surgery,School and Hospital of Stomatology,Jilin University,Changchun 130021,China)

机构地区：[1]吉林大学口腔医学院颌面外科,长春130021

出　　处：《实用肿瘤学杂志》2018年第3期258-262,共5页Practical Oncology Journal

基　　金：国家科技计划项目(编号:2016YFC1102805)

摘　　要：口腔鳞癌是口腔常见的恶性肿瘤。它具有浸润性生长,区域或远处淋巴转移和预后差的生物学特征。近年来,越来越多的研究发现长链非编码RNAs(Long non-coding RNAs,Lnc RNAs)在口腔鳞癌中异常表达并调节其生物学行为。本文就长链非编码RNAs在口腔鳞癌中的研究进展做一综述。Oral squamous cell carcinoma is a common malignancy in the oral cavity. It has biological features such as invasive growth,local or distant lymph node metastasis and poor prognosis. In recent years,more and more studies have found that Long non-coding RNAs（ Lnc RNAs） are abnormally expressed in oral squamous cell carcinoma and regulated its biological behavior. This article reviews the research progress of Lnc RNA in oral squamous cell carcinoma.

关 键 词：长链非编码RNA 口腔鳞癌 异常表达 

分 类 号：R739.8[医药卫生—肿瘤]