CT能谱成像在胃癌周围侵犯评价中的应用研究  

Application Study of Dual-source CT Dualenergy Imaging in the Diagnosis of Adjacent Structures in Gastric Cancer

作　　者：欧阳华忠[1] 尹红军[1] 贾文霄[2] 杜江华 王皓[3] 王云玲[3] OUYANG Hua-zhong;YIN Hong-jun;JIA Wen-xiao(Xinjiang Seventh Division Hospital of Production and Construction Corps,Xinjiang 830028,China)

机构地区：[1]新疆生产建设兵团第七师医院 [2]新疆医科大学 [3]新疆医科大学第二附属医院,新疆830000

出　　处：《中国CT和MRI杂志》2018年第7期129-132,共4页Chinese Journal of CT and MRI

基　　金：新疆维吾尔自治区自治区自然科学基金课题编号:2016D01C198

摘　　要：目的探讨双源CT双能量成像在胃癌周围侵犯诊断中的应用价值。方法收集我院病理确诊为胃癌的64例患者的临床资料,所有患者均行双源CT腹部常规平扫和能谱增强扫描,根据病理结果将淋巴结及脂肪组织分为转移组与无转移组,并分别测量并比较其双期标准化碘浓度(normalized iodine concentration,NIC)差异。结果转移淋巴结与非转移淋巴结动脉期的NIC值分别是(0.545±0.087)、(0.143±0.078),差异有统计学意义(P<0.05);静脉期的转移性淋巴结与非转移淋巴结NIC值分别是(0.478±0.014)、(0.306±0.083),差异有统计学意义(P<0.05)。动脉期标准化碘浓度>0.223时的诊断转移淋巴结灵敏度为69.8%,特异度为91.2%;静脉期标准化碘浓度>0.392的诊断灵敏度为78.3%,特异度为85.6%。受侵脂肪组织与未受侵脂肪组织动脉期的NIC值分别是(0.651±0.351)、(0.001±0.180),差异有统计学意义(P<0.05);静脉期NIC值分别是(1.081±0.429)、(0.170±0.251),差异有统计学意义(P<0.05)。动脉期标准化碘浓度>0.150时,诊断受侵断脂肪组织灵敏度为97.8%,特异度为86.7%;静脉期标准化碘浓度>0.620的诊断灵敏度为86.8%,特异度为98.8%。结论能量成像NIC值测定对胃癌周围侵犯的诊断有较大的帮助,可作为胃癌预后评估的量化指标。Objective To investigate the value of dual-source CT energy imaging in the diagnosis of peripheral gastric cancer invasion. Methods We collected the complete data of 64 patients who has been diagnosed with gastric cancer in our hospital, all patients underwent dual-source CT abdominal routine scanning and energy spectrum enhancement scans. According to the pathologic results, the lymph nodes and adipose tissue were divided into metastatic and non metastatic groups, then measured and compared the difference of standardized iodine concentrations（Normalized Iodine Concentration, NIC） between the metastatic and the non metastatic of gastric cancer respectively. Results The NIC value of metastatic lymph node artery was（0.545±0.087）, the non metastatic lymph node was（0.143±0.078）, and the difference was statistically significant（P〈0.05）. The metastatic lymph node NIC in venous period was（0.478±0.014）, and the non metastatic lymph nodes were（0.306±0.083）, the difference was statistically significant（P〈0.05）. When the standardized iodine concentration in arterial phase was 〉0.223, the sensitivity of the diagnostic lymph node was 69.8%, the specificity was 91.2%, and the diagnostic sensitivity was 78.3% and the specificity was 85.6% in the venous phase standardized iodine concentration 〉0.392. The NIC values of the affected adipose tissue and the unexposed fat tissue were（0.651±0.351） and（0.001±0.180） respectively, and the differences were statistically significant（P〈0.05）. The NIC value of venous period was（1.081±0.429） and（0.170±0.251）, and the difference was statistically significant（P〈0.05）. When the standardized iodine concentration in arterial phase was 0.150, the sensitivity of invasive adipose tissue was 97.8%, the specificity was 86.7%, and the diagnostic sensitivity was 86.8% and the specificity was 98.8% in the venous phase standardized iodine concentration 〉0.620. Conclusion The NIC value of energy imaging is helpful for the diagnosis of

关 键 词：胃癌 转移淋巴结 受侵脂肪 标准化碘浓度 

分 类 号：R735.2[医药卫生—肿瘤] R445.3[医药卫生—临床医学]