一种含有2-吡啶基噻吩的噻唑小分子的合成及其对HSO_3^-的识别  

Synthesis of Thiazole Small Molecule Containing 2-Pyridylthiophene and Its Recognition of HSO_3^-

作　　者：唐定国[1] 曾榕清 姚凯月 李襄宏[1] Tang Dingguo;Zeng Rongqing;Yao Kaiyue;Li Xianghong(College of Chemistry and Materials Science,South-Central University for Nationalities,Wuhan 430074,Chin)

机构地区：[1]中南民族大学化学与材料科学学院,武汉430074

出　　处：《中南民族大学学报（自然科学版）》2018年第2期20-23,共4页Journal of South-Central University for Nationalities：Natural Science Edition

基　　金：国家自然科学基金资助项目(21301196);湖北省自然科学基金资助项目(2012FFB07405)

摘　　要：以1-乙基碘化-2-甲基苯并噻唑为原料,合成了一种新的噻唑衍生物(化合物1),并通过~1H NMR和MS谱表征了其结构.以检测水溶液中HSO_3^-为目的,利用紫外-可见光谱研究了Cl^-,Br^-,NO_3^-,H_2PO_4^-,CO_3^(2-),HCO_3^-,ClO_4^-,SO_4^(2-),Ac^-,HS^-,HSO_3^-等常见阴离子对化合物1光谱的影响.结果表明:化合物1识别HSO_3^-,响应时间快、检测限低(0.21μmol·L^(-1));化合物1也能识别HS^-,其检测限为2.5μmol·L^(-1),但需较长的反应时间.因此,在短时间、低浓度下,HS^-对HSO_3^-的识别无明显干扰,此新的噻唑衍生物可用于快速选择性检测HSO_3^-.A new thiazole derivative（compound 1） was synthesized from 2-methyl-1-ethyl benzothiazole iodide, and then characterized by -1 H NMR and MS. For the purpose of detection of HSO3^-in aqueous solution, the interactions between the compound and some common anions,including Cl^-,Br^-,I^-,NO3^-,H2 PO4^-,CO3^2-,HCO3^-,ClO4^-,SO4^2-,Ac^-,HS^-and HSO3^-were studied by UV-Vis spectroscopy. The results showed that HSO3^-could be recognized by compound 1 with fast response time and low detection limit（0. 21μmol·L^-1）. Compound 1 also displayed recognition of HS^-with a detection limit of 2.5 μmol · L^-1, but the process took much longer time. Thus the presence of HS-presented no obvious interference for detecting HSO3^-in a short time and low concentration. The new thiazole derivative can therefore be used for the rapid and selective detection of HSO3^-.

关 键 词：亚硫酸氢根 硫氢根 噻唑衍生物 离子识别 

分 类 号：O625[理学—有机化学]