In vitro prebiotic effects of seaweed polysaccharides  

作　　者：CHEN Xiaolin SUN Yuhao HU Linfeng LIU Song YU Huahua XING Rong＇e LI Rongfeng WANG Xueqin LI Pengcheng 陈晓琳;孙雨豪;胡林峰;刘松;于华华;邢荣娥;李荣锋;王雪芹;李鹏程(Institute of Oceanology, Chinese Academy of Sciences;School of Chemistry & Chemical Engineering, Henan Institute of Science and Technology)

机构地区：[1]Institute of Oceanology,Chinese Academy of Sciences,Qingdao 266071,China [2]School of Chemistry ＆ Chemical Engineering,Henan Institute of Science and Technology,Xinxiang 453003,China

出　　处：《Journal of Oceanology and Limnology》2018年第3期926-932,共7页海洋湖沼学报（英文）

基　　金：Supported by the Commonwealth Item of the State Oceanic Administration of the People’s Republic of China(Nos.201405038-2,201505033);Qingdao People’s Livelihood Science and Technology Projects(No.16-6-2-41-nsh)

摘　　要：Although prebiotic activities of alginate and agar oligosaccharides isolated from seaweeds have been reported, it remains unknown whether seaweed polysaccharides have prebiotic activity. In this study, we isolated polysaccharides from four species of seaweeds, such as Grateloupia fi licina(GFP), Eucheuma spinosum(ESP), Ulva pertusa(UPP), and A scophyllum nodosum(ANP), and characterized their structures and prebiotic ef fects in vitro. The results showed that these polysaccharides were dif ferent in total sugar and sulfate contents as well as monosaccharide composition. GFP and ESP significantly promoted bifi dobacterium proliferation and 0.1% ESP and 0.4% GFP resulted in the highest proliferation rates of beneficial bacteria, whereas UPP and ANP inhibited the growth of beneficial bacteria at all tested concentrations(0.1%–0.5%). The different behaviors of the four seaweed-originated polysaccharides might be refl ected by differences in monosaccharide composition and structure. Therefore, polysaccharides isolated from GFP and ESP could be utilized as prebiotics. However, more studies must be carried out in vivo.Although prebiotic activities of alginate and agar oligosaccharides isolated from seaweeds have been reported, it remains unknown whether seaweed polysaccharides have prebiotic activity. In this study, we isolated polysaccharides from four species of seaweeds, such as Grateloupia fi licina（GFP）, Eucheuma spinosum（ESP）, Ulva pertusa（UPP）, and A scophyllum nodosum（ANP）, and characterized their structures and prebiotic ef fects in vitro. The results showed that these polysaccharides were dif ferent in total sugar and sulfate contents as well as monosaccharide composition. GFP and ESP significantly promoted bifi dobacterium proliferation and 0.1% ESP and 0.4% GFP resulted in the highest proliferation rates of beneficial bacteria, whereas UPP and ANP inhibited the growth of beneficial bacteria at all tested concentrations（0.1%–0.5%）. The different behaviors of the four seaweed-originated polysaccharides might be refl ected by differences in monosaccharide composition and structure. Therefore, polysaccharides isolated from GFP and ESP could be utilized as prebiotics. However, more studies must be carried out in vivo.

关 键 词：polysaccharides seaweed prebiotic effects in vitro antibacterial ACTIVITY 

分 类 号：Q949.254[生物学—植物学]