血清降钙素原含量与急性脑梗死的关系  

Relationship between serum PCT and acute cerebral infarct

作　　者：刘运宝[1] 李素芹[2] 李应宏[1] 王霞[1] 李德中[2] 刘勇 LIU Yun-bao;LI Su-qin;LI Ying-hong;WANG Xia;LI De-zhong;LIU Yong(Department of Clinical Neurology,Pangang Group General Hospital,Panzhihua,Sichuan,617000 China)

机构地区：[1]攀钢集团总医院神经内科,四川攀枝花617000 [2]攀钢集团总医院检验科,四川攀枝花617000

出　　处：《中国冶金工业医学杂志》2018年第4期384-386,共3页Chinese Medical Journal of Metallurgical industry

摘　　要：目的探讨降钙素原(PCT)在急性脑梗死治疗中的应用价值。方法选取本院神经内科2015年1月至2016年6月首次发病的急性脑梗死住院患者82例为研究组,其中发热69例,以体温39.0℃为界,分为高体温组18例,低体温组51例;同期中老年体检者80例作为对照组,检测血清PCT含量,结合临床资料及统计学分析结果,评价血清PCT含量与急性脑梗死的关系。结果研究组PCT含量显著高于对照组(P<0.001),高体温组PCT含量显著高于低体温组和体温正常组(P<0.01)。结论血清PCT含量测定可指导急性脑梗死患者的抗生素使用,以减少抗生素的使用及耐药性发生,降低死亡率、致残率。Objective To explore the value of serum procalcitonin（PCT）in the treatment of acute cerebral infarct. Methods 82 hospitalized patients with acute cerebral infarct from January 2015 to June 2016 were chosen as research group,including 69 of persistent fever which were divided into high temperature group（n=18）and low temperature group（n=51）according to 39.0℃. 80 middle-old aged with medical examination were collected as control group. Levels of serum PCT were detected,and relationship between the efficacy and 1 evels of serum PCT and acute cerebral infarct were evaluated combined with the clinic data and statistical analysis results. Results Levels of serum PCT in the research group were significantly higher than those in the control group（P〈0.001）.Levels of serum PCT in the high temperature group were significantly higher than those in the low temperature group and the control group（P〈0.01）.Conclusion Serum PCT can be used for the antibiotics choice in acute cerebral infarct with high fever,so that reduce the amount,resistance of antibiotics and decrease mortality and disability.

关 键 词：降钙素原 脑梗死 关系 

分 类 号：R743.3[医药卫生—神经病学与精神病学]