1990和2015年天津市脑卒中死亡率和疾病负担分析  

Analysis on mortality and disease burden of stroke in Tianjin in 1990 and 2015

作　　者：刘明法 周脉耕[2] 刘世炜[2] 曾新颖[2] 张辉[3] 徐忠良[3] 王德征[3] LIU Ming-fa;ZHOU Mai-geng;LIU Shi-wei;ZENG Xin-ying;ZHANG Hui;XU Zhong-liang;WANG De-zheng(Department of Chronic Diseases Control and Prevention,Tianjin Binhai New Area Center for Disease Control and Prevention,Tianjin 300451,China;National Center for Chronic and Non-communicable Diseases Control and Prevention,Chinese Center for Disease Control and Prevention,Beijing 100050,China;Department of Non-communicable Diseases Control and Prevention,Tianjin Centers for Disease Control and Prevention,Tianjin 300011,China)

机构地区：[1]天津市滨海新区疾病预防控制中心慢性病预防与控制科,300451 [2]中国疾病预防控制中心慢性非传染性疾病预防控制中心综合防控与评价室,北京100050 [3]天津市疾病预防控制中心非传染病预防控制室,300011

出　　处：《中国现代神经疾病杂志》2018年第7期520-526,共7页Chinese Journal of Contemporary Neurology and Neurosurgery

基　　金：天津市卫生局科技基金资助项目(项目编号:2013KY22)~~

摘　　要：目的分析1990和2015年天津市脑卒中死亡率以及疾病负担的变化趋势。方法利用2015年全球疾病负担研究中国分省结果,采用死亡例数、死亡率以及伤残调整寿命年(DALY)、因早死所致的寿命损失年(YLL)、残疾所致的健康寿命损失年(YLD)作为疾病负担的主要指标,比较1990和2015年天津市脑卒中死亡率和疾病负担变化。结果 2015年天津市脑卒中死亡率为101.53/10万,标化死亡率为117.73/10万,其造成的DALY、YLL和YLD分别为285 558.36、265 627.77和19 930.60人年,标化DALY率、YLL率和YLD率分别为1870.55/10万、1746.63/10万和123.92/10万;与1990年相比,2015年脑卒中死亡例数、DALY、YLL和YLD分别增加26.24%、9.05%、5.48%和98.63%,而标化死亡率、DALY率、YLL率和YLD率分别下降46.75%、52.81%、54.32%和11.20%。1990和2015年天津市出血性卒中DALY、YLL高于,YLD低于缺血性卒中;与1990年相比,2015年天津市出血性卒中DALY降低11.77%、YLL降低14.75%、YLD增加96.87%,缺血性卒中DALY增加47.38%、YLL增加44.04%、YLD增加100.08%。结论天津市脑卒中疾病负担越来越严重,尤其是缺血性卒中,且男性疾病负担重于女性。Objective To analyze the changes of mortality and disease burden of stroke in 1990 and 2015 in Tianjin. Methods The results of the Global Burden of Diseases Study 2015（GBD 2015） forChinese estimated by province were used to describe the disease burden of stroke in Tianjin. The analysisindex included number of death, mortality rate, disability adjusted life year（DALY）, years of life lost（YLL）and years lost due of disability（YLD）. The change from 1990 to 2015 for all indexes was used to describethe transitions of disease burden of stroke in the past 25 years in Tianjin. Results In 2015, the mortalityrate of stroke reached 101.53 per 100 000 people and the age-standardized mortality rate was 117.73 per100 000 people. The DALY, YLL, and YLD reached 285 558.36, 265 627.77 and 19 930.60 person year,respectively, and the age-standardized DALY rate, YLL rate and YLD rate were 1870.55, 1746.63 and123.92 per 100 000 people. Compared with the result in 1990, the number of death, DALY, YLL and YLDin 2015 were increased by 26.24%, 9.05%, 5.48% and 98.63%, respectively, while the age-standardizedmortality rate, DALY rate, YLL rate and YLD rate in 2015 were decreased by 46.75%, 52.81%, 54.32% and 11.20%, respectively. In different types of stroke, DALY and YLL of hemorrhagic stroke were higher,while YLD was lower than ischemic stroke in 1990 and 2015. Compared with 1990, DALY was decreased by 11.77%, YLL was decreased by 14.75%, and YLD was increased by 96.87% in hemorrhagic stroke in 2015, while DALY was increased by 47.38%, YLL was increased by 44.04% and YLD was increased by 100.08% in ischemic stroke in 2015. Conclusions Disease burden of stroke became more and moreserious in Tianjin, of which the ischemic stroke was most serious, and the disease burden of stroke in menwas greater than that in women.

关 键 词：卒中 死亡率 患病代价 天津 流行病学研究 

分 类 号：R743.3[医药卫生—神经病学与精神病学]