肝细胞肝癌微血管侵犯的MRI研究  

The study of microvascular invasion of hepatocellular carcinoma with MRI

作　　者：王家臣[1] 牛蕾[1] 段崇锋[1] 焦琳琳[2] 周晓明[1] 王刚[1] 于海洋[1] WANG Jiachen;NIU Lei;DUAN Chongfeng;JIAO Linlin;ZHOU Xiaoming;WANG Gang;YU Haiyang(Department of Radiology,The Affiliated Hospital of Qingdao University,Qindao 266555,P.R.China;Medical Center Intervention,The Affiliated Hospital of Qingdao University,Qindao 266555,P.R.China)

机构地区：[1]青岛大学附属医院放射科,山东青岛266555 [2]青岛大学附属医院介入医学中心,山东青岛266555

出　　处：《医学影像学杂志》2018年第6期971-974,共4页Journal of Medical Imaging

摘　　要：目的探讨肝细胞肝癌微血管侵犯(MVI)与MRI影像特征的相关性。方法回顾分析107例肝细胞肝癌患者的MRI动态增强图像,研究肿瘤大小、动脉期瘤周增强、肿瘤包膜、肿瘤边缘以及多灶性与肝细胞肝癌微血管侵犯的相关性。确定MVI的独立预测因子。结果 MVI阳性的有31.8%(34/107),MVI阴性的为68.2%(73/107)。两组之间动脉期瘤周增强、肿瘤包膜以及多灶性无统计学差异(P>0.05);肿瘤大小、肿瘤边缘有统计学差异(P<0.05)。结论肿瘤大于5cm和边缘不光滑可以术前预测肝细胞肝癌MVI。Objective To investigate the correlation between Microvascular invasion （MVI） and MRI image features in in patients withhepatocellular carcinoma （HCC）. Methods The MRI dynamic congteast-enhanced images of 107 patients with hepatocellular carcinomawere reviewed retrospectively. The correlation between tumorsize, peritumoral arterial enhancement,tumor pseudo-capsule, tumormargins,multifocality and microvascular invasion of hepatocellular carcinoma were studied and independent predictors of MVI were determind. Results 31.8%（34/107） of the patients with HCC were confirmed as MVI-positive, and 68.2%（73/107） were as MVI-negative. There were no statistically significant difference between the two groups in peritumoral arterial enhancement, tumor pseudo-capsule and multifocality （ P 〉0.05）, and there were statistically significant difference in tumor size and tumor margin （ P 〈0.05）. Conclusion A tumor size 〉5 cm and a non-smooth tumor margin could be used as preoperative predictors of the presence of MVI in patients with HCC.

关 键 词：肝细胞癌 磁共振成像 微血管侵犯 

分 类 号：R735.7[医药卫生—肿瘤] R445.2[医药卫生—临床医学]