孤独症谱系障碍男童共情能力特点以及与睾酮水平的关系  

The relationship with characteristics of empathy and testosterone level in boys with autism spectrum disorders

作　　者：邱久军 陈冬梅 周利冰 林力孜 戴美霞[3] 夏志鹏 詹萍 龚建华 静进[3] QIU Jiu-jun;CHEN Dong-mei;ZHOU Li-bing(Department of Children Health Care,Shenzhen Luohu District Maternal and Child Health Care Hospital,Shenzhen 518000,China)

机构地区：[1]深圳市罗湖区妇幼保健院儿童保健科,518000 [2]深圳市妇幼保健院儿童心理与康复科,518028 [3]中山大学公共卫生学院妇幼卫生系,510080

出　　处：《中国实用医药》2018年第21期13-16,共4页China Practical Medicine

基　　金：深圳市科技创新委员会(项目编号:JCYJ20150403142731427)

摘　　要：目的研究孤独症谱系障碍(ASD)男童共情能力结构特点及其与血清睾酮的相关性。方法 200例4~11岁ASD男童(ASD组)及200例正常男童(对照组)作为研究对象,采用儿童同理心-系统化商数问卷评估同意共情能力较好、不同意共情受损情况及同意系统化能力较好、不同意系统化受损情况以得出共情商(EQ)和系统化商(SQ)两个维度的能力。同时进行血清睾酮检测,分析ASD男童共情能力特点以及血清睾酮水平与共情能力相关性。结果 ASD组EQ得分(19.17±4.70)分明显低于对照组的(27.50±6.53)分,差异有统计学意义(P<0.05);ASD组SQ得分(22.17±7.25)分与对照组(23.17±5.41)分比较差异无统计学意义(P>0.05);ASD组EQ和SQ中不同意受损方面(15.50±5.64)、(11.01±4.51)分明显高于对照组的(8.83±7.46)、(3.50±2.88)分,同意能力较好方面(3.67±2.94)、(9.17±8.08)分则低于对照组的(18.01±4.85)、(19.67±7.58)分,差异均有统计学意义(P<0.05)。两组的EQ与SQ得分比较差异无统计学意义(P>0.05)。ASD组睾酮水平为(2.10±1.77)ng/ml,对照组为(2.08±1.07)ng/ml,比较差异无统计学意义(P>0.05)。ASD组的睾酮水平与EQ呈负相关(r=-0.36,P<0.05)、与SQ无明显相关(P>0.05);对照组的睾酮水平与EQ、SQ都无关(P>0.05)。结论在4~11岁ASD男童存在共情能力低下,睾酮水平越高共情能力越低,和系统化能力并无明显对立。ASD家长在对共情及系统化能力的认知方面与正常儿童家长有明显差异。Objective To study the relationship with characteristics of empathy and testosterone level in boys with autism spectrum disorders. Methods 200 cases of 4-11 years old ASD boys（ASD group） and 200 normal boys（control group） were selected as research objects. The ability of two dimensions of empathy quotient（EQ） and systemizing quotient（SQ） were obtained by using the children＇s empathy quotient and systemizing quotient questionnaire to evaluate the ability of agreeing with good empathy, the damage of disagreeing with empathy and the ability of agreeing with good systematization, the damage of disagreeing with systematized. The serum testosterone at the same time was detected. The characteristics of empathy and the correlation between serum testosterone and empathy ability were analyzed in ASD boys. Results The EQ score of the ASD group was（19.17±4.70） scores, which was significantly lower than（27.50±6.53） scores of the control group, the difference was statistically significant（P〈0.05）. The SQ score of the ASD group was（22.17±7.25） scores, compared with（23.17±5.41） scores of the control group, there was no statistically significant difference（P〉0.05）. In the ASD group, the damage of disagreeing with EQ and SQ were（15.50±5.64） scores and（11.01±4.51） scores respectively, which were significantly higher than（8.83±7.46） scores and（3.50±2.88） scores in the control group, the agreeing with good EQ and SQ in the ASD group were（3.67±2.94） scores and（9.17±8.08） scores, which were significantly lower than（18.01±4.85） scores and（19.67±7.58） scores in the control group, the differences were statistically significant（P〉0.05）. There were no significant differences in the scores of EQ and SQ between the two groups（P〉0.05）. The testosterone level in the ASD group was（2.10±1.77） ng/ml, and that of the control group was（2.08±1.07） ng/ml, the difference was not statistically significant（P〈0.05）. The testosterone level

关 键 词：孤独症谱系障碍 共情 系统化 睾酮 

分 类 号：R749.94[医药卫生—神经病学与精神病学]