饮食、环境危险因素与前列腺穿刺活检阳性的关联  

Relationship between dietary and environment risk factors and positive puncture biopsy of prostate

作　　者：张连升 郭伟[2] 金鑫 王振杰 徐永干 ZHANG Lian-sheng;GUO Wei;JIN Xin;WANG Zhen-jie;XU Yong-gan(Urology Department,Xinghua City People＇s Hospital,Taizhou 225700;Jiangsu Taizhou People＇s Hospital,Taizhou225700,China)

机构地区：[1]兴化市人民医院泌尿外科,江苏泰州225700 [2]泰州市人民医院,江苏泰州225700

出　　处：《临床医学研究与实践》2018年第23期95-96,99,共3页Clinical Research and Practice

基　　金：泰州市科研基金(No.tz201748)

摘　　要：目的探讨泰州地区饮食、环境危险因素与前列腺穿刺活检阳性间的关联。方法回顾性分析泰州市人民医院及兴化市人民医院2015年1月至2018年1月收治的283例行前列腺穿刺活检患者的临床资料,根据穿刺结果分为前列腺癌组与非前列腺癌组。比较两组患者的年龄、前列腺特异抗原(PSA)、体重指数(BMI)等指标,并分析前列腺穿刺阳性的危险因素。结果两组患者的年龄、BMI比较,差异无统计学意义(P>0.05)。前列腺癌组患者的PSA显著高于非前列腺癌组,差异具有统计学意义(P<0.05)。前列腺癌组患者的吸烟者比例大于非前列腺癌组,体育锻炼、吃绿色蔬菜者比例小于非前列腺癌组(P<0.05)。结论综合考虑患者PSA及食用绿色蔬菜、吸烟、体育锻炼等因素可为前列腺癌的早期筛查及前列腺穿刺方案的制定提供重要信息,对泰州地区高危人群的早期预防、诊断、治疗提供重要依据。Objective To explore the association between dietary and environment risk factors and positive puncture biopsy of prostate in Taizhou. Methods The clinical data of 283 patients undergoing prostate biopsy from January 2015 to January 2018 in Taizhou people＇s hospital and Xinghua city people＇s hospital were retrospectively analyzed. Patients were divided into prostate cancer group and non-prostate cancer group by biopsy results. The indicators of age, level of prostate-specific antigen（PSA）, BMI of the two groups were compared. The risk factors for positive puncture biopsy of prostate were analyzed. Results There were no significant differences in age and BMI between the two groups（P0.05）.The PSA of the prostate cancer group was significantly higher than that of the non-prostate cancer group, the difference was statistically significant（P0.05）. The proportion of smokers in the prostate cancer group was greater than that in the non-prostate cancer group, the proportions of patients who exercised and ate green vegetables were smaller than those of the non-prostate cancer group（P0.05）. Conclusion Comprehensive consideration of patients with PSA and eating green vegetables, smoking, physical exercise and other factors can provide important information for early screening of prostate cancer and establishment of prostate biopsy scheme, which also can provide significant evidence for the prevention,diagnosis and treatment of prostate cancer at early stage for high risk population in Taizhou.

关 键 词：前列腺癌 饮食、环境因素 前列腺穿刺 活检阳性 

分 类 号：R737.25[医药卫生—肿瘤]