焦虑及抑郁评分与慢性便秘患者临床不同伴随症状关系研究  

Relationship of anxiety,depression score with different clinical symptoms in patients with chronic constipation

作　　者：窦迎春[1] 曲海霞[2] 许倩倩[1] 李青[1] 马健[1] 周长宏[1] 于新娟[3] 孟欣颖[1] DOU Yingchun;QU Haixia;XU Qianqian;LI Qing;MA Jian;ZHOU Changhong;YU Xinjuan;MENG Xinying(Department of Heahhcare;Department of Gastroenterology;Central Laboratory,Qingdao（East）,the Affiliated Hospital of Qingdao University,Qingdao 266071,China)

机构地区：[1]青岛大学医学院附属青岛市市立医院(东区)干部保健科,山东青岛266071 [2]青岛大学医学院附属青岛市市立医院(东区)消化内科,山东青岛266071 [3]青岛大学医学院附属青岛市市立医院(东区)中心实验室,山东青岛266071

出　　处：《胃肠病学和肝病学杂志》2018年第8期896-899,共4页Chinese Journal of Gastroenterology and Hepatology

摘　　要：目的探讨焦虑、抑郁评分与慢性便秘患者临床不同伴随症状的关系。方法收集2017年2月至2017年8月于青岛市市立医院干部保健科就诊且符合慢性便秘诊断标准的患者(研究组)49例,男29例,女20例,同时选取34例无便秘患者作为对照组,男18例,女16例。运用焦虑自评量表(SAS)、抑郁自评量表(SDS)评估两组患者焦虑、抑郁评分之间的差异。结果慢性便秘患者的SAS评分为43.03±7.19、SDS评分为45.38±9.56,高于无便秘患者的SAS评分38.39±6.56、SDS评分38.54±7.27,差异有统计学意义(tSAS=2.571,PSAS=0.013;tSDS=3.005,PSDS=0.004);女性便秘患者SAS评分为47.21±7.31,高于男性便秘患者的SAS评分40.41±5.85,差异有统计学意义(t=3.212,P=0.003),而女性与男性便秘患者SDS积分相比,差异无统计学意义(t=0.738,P=0.465);对于慢性便秘患者临床不同伴随症状,伴有腹痛的慢性便秘患者SDS评分为48.60±8.98高于对照组38.94±7.36,差异有统计学意义(t=3.347,P=0.002),伴有腹痛的慢性便秘患者SAS评分与对照组患者相比,差异无统计学意义(t=1.659,P=0.105);伴或不伴有腹胀、排便费力、排便不尽感的慢性便秘患者SAS评分、SDS评分相比,差异均无统计学意义(P>0.05)。结论慢性便秘患者与无便秘患者相比,焦虑、抑郁评分较高,性别、腹痛与慢性便秘患者焦虑、抑郁状态有一定关系。Objective To investigate the relationship of anxiety,depression score with different clinical symptoms in patients with chronic constipation. Methods A total of 49 patients with chronic constipation were enrolled from Feb. to Aug. 2017 in Qingdao Municipal Hospital,including 29 males and 20 females. And a total of 34 patients without chronic constipation were as control group,including 18 males and 16 females. Self-rating anxiety scale（SAS）,Self-rating depression scale（SDS） were used to assess the difference between two groups. Results The SAS score and SDS score in patients with chronic constipation（SAS： 43. 03 ± 7. 19,SDS： 45. 38 ± 9. 56） were obviously higher than those in patients without chronic constipation（SAS： 38. 39 ± 6. 56,SDS： 38. 54 ± 7. 27）,the difference was statistically significant（tSAS= 2. 571,PSAS= 0. 013; tSDS= 3. 005,PSDS= 0. 004）. The SAS score in female patients with chronic constipation was（47. 21 ± 7. 31） higher than that in the male patients with chronic constipation（40. 41 ± 5. 85）,and the difference was statistically significant（t = 3. 212,P = 0. 003）. However,there was no significant difference in SAS score between female and male patients with chronic constipation（t = 0. 738,P = 0. 465）. As different clinical symptoms in patients with chronic constipation,the SDS score in chronic constipation patients with abdominal pain was（48. 60 ± 8. 98） higher than that in the control group（38. 94 ± 7. 36）,the difference was statistically significant（t =3. 347,P = 0. 002）,and there was no significance difference between two group in SDS score（t = 1. 659,P = 0. 105）;SAS score and SDS score in patients with or without abdominal distension,defecation difficulty,defecation imcompletion were not statistically significant（P 〉0. 05）. Conclusion Patients with chronic constipation have higher scores of anxiety and depression,there is a certain relationship between the gender or abdominal pain and the anxiety or depression.

关 键 词：焦虑 抑郁 慢性便秘 性别 腹痛 

分 类 号：R574.62[医药卫生—消化系统]