综合康复治疗对复发性抑郁症患者康复效果1年随访研究  

1 year follow-up study on the effect of comprehensive rehabilitation therapy in patients with recurrent depression

作　　者：刘红霞[1] 高彩凤[1] 仇春革[1] 谷传正[1] 李龙飞[1] LIU Hong-xia;GAO Cai-jbng;QIU Chun-ge;GU Chuan-zheng;LI Long-fei(Jining Psychiatric Hospital,Jining 272051,China)

机构地区：[1]山东济宁市精神病防治院,272051

出　　处：《临床精神医学杂志》2018年第4期266-269,共4页Journal of Clinical Psychiatry

摘　　要：目的:探讨综合康复治疗对复发性抑郁症患者康复效果。方法:120例复发性抑郁症患者随机分为研究组和对照组,两组在药物治疗的基础上分别给予综合康复训练及一般康复指导,疗程3个月。入组时和3个月后分别给予汉密尔顿抑郁量表(HAMD)、精神病患者康复疗效评定量表(IPROS)、日常生活能力量表(ADL)、社会功能缺陷量表(SDSS)评估;1年后随访,比较两组服药依从性、复发率和再住院率。结果:研究组完成50例,对照组完成48例。入组时两组HAMD、IPROS、ADL及SDSS评分比较差异无统计学意义;3个月后,两组HAMD评分较入组时显著减低,且研究组显著低于对照组(P均<0.01);研究组IPROS总分及各因子分、SDSS评分较入组时及对照组显著减低,ADL显著提高(P<0.05或P<0.01);对照组与入组时比较差异无统计学意义。随访1年时,服药依从性研究组完全依从32例(64.00%)、部分依从10例(20.00%)、不依从8例(16.00%),对照组分别为27.08%、35.42%、37.50%;研究组服药总依从率显著高于对照组(χ2=5.81,P<0.05)。研究组复发率(16.00%)和再住院率(10.00%)显著低于对照组(39.58%,29.17%)(χ2=6.82,P<0.01;χ2=5.76,P<0.05)。结论:综合康复训练可提高复发性抑郁症患者的疗效、生活质量、社会功能及服药依从性,降低复发率和再住院率。Objective： To evaluate the efficacy of comprehensive rehabilitation therapy on rehabilitation of patients with recurrent depression. Method： One hundren and twenty patients with recurrent depression were randomly divided into study group and control group. The two groups were given comprehensive rehabilitation training and general rehabilitation guidance respectively on the basis of drug therapy for 3 months. At the time of enrollment and 3 months later,the patients were assessed by Hamilton depression scale（HAMD）,inpatients psychiatric rehabilitation observing scale（IPROS）,activity of daily living scale（ADL） and social disability screen scale（SDSS）. 1 year later,the compliance,recurrence rate and re-hospitalization rate were compared between the two groups. Results： Fifty cases in the study group and 48 cases in the control group completed the study. There were no significant differences between the two groups in scores of HAMD,IPROS,ADL and SDSS. After 3 months,the HAMD scores of the two groups were significantly lower than those at baseline,and the study group showed significantly lower HAMDscore than the control group（all P〈0. 01）. Total score and each factor score of IPROS,SDSS in the study group were significantly lower and the score of ADL was signifcantly higher than those at baseline and in the control group（P〈0. 05 or P〈0. 01）; but there were no significant differences between the baseline and 3 months later in the control group. One year later,medication adherence including complete compliance,partial compliance,non compliance in the study group were 32 cases（64%）,10 cases（20%） and 8 csaes（16%）,respectively; and 27. 08 %,35. 42 % and 37. 50 %,respectively in the control group. The total compliance rate in the study group was significantly higher than the control group（χ^2= 5. 81,P〈0. 05）. The rates of relapse and rehospitalization in the study group（16. 00%,10%）were significantly lower than the control group（39. 58%,29. 17%）（χ^2= 6. 82,P

关 键 词：复发性抑郁症 综合康复治疗 

分 类 号：R749.4[医药卫生—神经病学与精神病学]