经尿道钬激光膀胱肿瘤切除术治疗浅表性膀胱肿瘤的临床分析  

Transurethral holmium laser nephrectomy for superficial bladder tumor

作　　者：杨勇 王柱红 邱春明 张国飞 类成勇[2] Yang Yong;Wang Zhuhong;Qiu Chunming;Zhang Guofei;Lei Chengyong(Department of Urology,Nanhai Hospital,Southern Medical University,Foshan 528244,Chin;Department of Urology,Nanfang Hospital,Southern Medical University,Guangzhou 510515,Chin)

机构地区：[1]南方医科大学南海医院泌尿外科,佛山528244 [2]南方医科大学南方医院泌尿外科,广州510515

出　　处：《国际医药卫生导报》2018年第16期2431-2434,共4页International Medicine and Health Guidance News

基　　金：佛山市自筹经费类科技计划项目（2017AB000662）

摘　　要：目的 观察评价经尿道钬激光膀胱肿瘤切除术（HOLRBT）与经尿道膀胱肿瘤电切术（TURBT）治疗浅表性膀胱肿瘤（SBC）的临床效果.方法 选择2013年1月至2016年3月期间收治的浅表性膀胱肿瘤患者122例,并随机对照试验分为两组;对照组61例给予TURBT治疗,观察组61例给予HOLRBT治疗,并比较两组的临床效果.结果 两组患者手术时间差异无统计学意义;观察组术中出血量、膀胱冲洗时间、尿管留置时间、住院时间及并发症发生率均显著低于对照组（均P＜ 0.05）;观察组总复发率为8.20％,明显低于对照组的16.39％（P＜0.05）;两组治疗前SF-36评分差异无统计学意义（P＞0.05）,治疗后两组SF-36评分均明显升高,但观察组生理功能、躯体功能、情感职能、社会功能及总体健康评分均显著高于对照组（均P＜ 0.05）.结论 HOLRBT治疗SBC能够减少术中出血量,大大缩短了膀胱冲洗时间、尿管留置时间及住院时间,有效降低并发症发生率及复发率,并提高生活质量,值得临床大力推广.Objective To observe and evaluate the clinical effects of transurethral holmium laser resection of bladder tumor （HOLRBT） and transurethral resection of bladder tumor （TURBT） in the treatment of superficial bladder tumor （SBC）.Methods A total of 122 patients with superficial bladder tumor treated at our hospitals from January,2013 to March,2016 were selected,and randomly divided into a control group and an observation group,61 for each group.The control group were treated with TURBT,and the observation group HOLRBT.The clinical effects of the two groups were compared.Results There was no significant difference in operation time between the two groups （P〉0.05）.The intraoperative bleeding volume,bladder irrigation time,catheter indwelling time,length of hospital stay,and complication rate were significantly lower in the observation group than in the control group （all P〈 0.05）.The total recurrence rate was significantly lower in the observation group than in the control group （8.20%,P〈 0.05）.There were no statistical differences in SF-36 scores between these two groups before the treatment （P〉0.05）.After treatment,the SF-36 scores increased significantly in both groups;and the scores of physiological function,physical function,emotional function,social function,and overall health were significantly higher in the observation group than in the control group （P〈 0.05）.Conclusion HOLRBT for SBC can reduce the intra-operative bleeding volume,greatly shorten the bladder irrigation time,catheter retention time,and length of stay,effectively decrease the incidence of complications and recurrence rate,and improve the quality of life,so it is worth for clinical promotion application.

关 键 词：浅表性膀胱肿瘤 经尿道钬激光膀胱肿瘤切除术 经尿道膀胱肿瘤电切术 

分 类 号：R737.14[医药卫生—肿瘤]