吲哚菁绿试验联合Child-Pugh分级评估老年肝细胞癌患者围术期肝功能储备的价值  

The value of indocyanine green test combined with Child-Pugh classification in evaluating perioperative liver function reserve in elderly patients with hepatocellular carcinoma

作　　者：周元[1] 陈橼[1] 尹必辉 周益龙[1] 邵冰峰[1] 张素青[1] 张一心[1] 陈冰燕 ZHOU Yuan;CHEN Yuan;YIN Bi-hui;ZHOU Yi-long;SHAO Bing-feng;ZHANG Su-qing;ZHANG Yi-xin;CHEN Bing-yan(Department of Surgery,Nantong Tumour Hospital,Nantong University,Nantong 226300,Jiangsu,China;The Oncology Department of Clinical Medicine,Nantong University Oncology,Nantong 226019,Jiangsu,China;Department of Laboratory,Nantong Tumour Hospital,Nantong University,Nantong 226300,Jiangsu,China)

机构地区：[1]南通大学附属肿瘤医院外科,南通226300 [2]南通大学医学院研究生院临床医学系,南通226019 [3]南通大学附属肿瘤医院检验科,南通226300

出　　处：《中国临床医学》2018年第3期400-404,共5页Chinese Journal of Clinical Medicine

基　　金：江苏省南通市卫计委重点病种的临床规范化诊疗项目(MS32015028);江苏省南通市卫计委医学重点学科建设(YY201207)~~

摘　　要：目的:探讨吲哚菁绿(indocyanine green,ICG)试验联合Child-Pugh分级联合评估老年原发性肝细胞癌(简称肝癌)手术患者肝功能储备的可行性。方法:选择2008年1月至2012年12月接受肝癌手术的患者104例,采用Child-Pugh分级和(或)联合吲哚氰绿15min潴留率(ICG R15)评估老年患者肝功能储备,分析术后患者肝功能恢复情况和联合评估的价值。结果:ICG R15与Child-Pugh评分正相关(r=0.81,P<0.0001);经联合评分系统评估的患者术后恢复优于单独Child-Pugh分级患者。结论:ICG R15联合Child-Pugh评估老年肝癌患者肝功能储备的效果优于单用Child-Pugh分级。Objective： To investigate the value of indocyanine green（ICG）test combined with Child-Pugh classification in evaluating perioperative liver function reserve in elderly patients with hepatocellular carcinoma（HCC）.Methods：A total of 104 elderly patients with HCC treated in our hospital from January 2008 to December 2012 were selected.The liver function was evaluated by Child-Pugh classification or Child-Pugh classification combined with ICG R15 in these patients before operation,and the liver function after operation and the value of combination assessment were analyzed.Results：There was positive correlation between ICG R15 score Child-Pugh（r=0.81,P〈0.0001）.Patients evaluated by Child-Pugh classification combined with ICG R15 had a better post-operation recovery than those evaluated by Child-Pugh classification alone.Conclusions： Child-Pugh classification combined with ICG R15 might be superior to Child-Pugh classification alone in evaluating perioperative liver function reserve in elderly patients with HCC.

关 键 词：CHILD-PUGH分级 吲哚菁绿 肝功能储备 肝细胞癌 

分 类 号：R735.7[医药卫生—肿瘤]