三孔法腹腔镜根治性前列腺切除术在进展性前列腺癌治疗中的应用研究  

Application of three-hole laparoscopic radical prostatectomy in the treatment of advanced prostate cancer

作　　者：雷永东 刘小勇[2] 向宸辉[2] LEI Yong-dong;LIU Xiaoyong;XIANG Chenhui(Department of Urinary Surgery,Chengdu Beixin Hospital,Chengdu,Sichuan 610500,China;Department of Urinary Surgery,The First Affiliated Hospital of Chengdu Medical College,Chengdu,Sichuan 610500,China)

机构地区：[1]成都北新医院泌尿外科,四川610500 [2]成都医学院第一附属医院泌尿外科,四川成都610500

出　　处：《现代医药卫生》2018年第13期1986-1988,共3页Journal of Modern Medicine & Health

摘　　要：目的研究三孔法腹腔镜根治性前列腺切除术(RP)治疗进展性前列腺癌(PC)的临床效果。方法选择2013年7月至2016年6月于成都医学院第一附属医院治疗的进展性PC患者84例,按照随机数字表法分为腹腔镜组与开放组,各42例,腹腔镜组行三孔法腹腔镜RP,开放组行开放RP。观察两组术中出血量,手术时间,术后尿管留置时间,术后住院时间,术后1、6个月控尿程度及性功能,术后1年生化复发情况,术后并发症发生情况。结果腹腔镜组术中出血量、手术时间、术后尿管留置时间、术后住院时间均低于开放组,差异均有统计学意义(P<0.05)。两组术后1、6个月控尿程度、性功能得分比较,差异均无统计学意义(P>0.05)。腹腔镜组术后1年生化复发率与开放组比较,差异无统计学意义(P>0.05)。腹腔镜组术后并发症发病率低于开放组,差异有统计学意义(P<0.05)。结论三孔法腹腔镜RP创伤小,术后并发症发病率低,且可达到与开放治疗相同的疗效,值得临床应用。Objective To study the clinical effect of radical prostatectomy （RP） for progressive prostate cancer （PC）. Methods 84 cases of progressive PC patients treated in the First Affiliated Hospital of Chendu Medical College from July 2013 to June 2016 were selected, divided into laparoscope group （n=42） and open group （n=42） according to the random number table method. Patients in laparoscope group were treated by three-hole laparoscopic RP, and patients in open group ,were treated by open RP. The intraoperative bleeding volume, operation time, indwelling catheter time, the time of hospitalization, the degree of urinary continence and sexual function after 1,6 months after operation, 1 year after operation biochemical recmTence and postoperative complications were observed. Results The intraoperative bleeding volume, operation time, indwelling catheter time, the time of hospitalization in laparoscope group were lower than those in open group, the differences were statistically sig- nificant （P〈0.05）. The degree of urinary continence and sexual function after 1,6 months after operation between two groups ,were compared, the differences were not statistically significant （P〉0.05）. The biochemical recmTence rate after 1-years in the laparoscopic group was not significantly different from the open group （P〉0.05）. The incidence of postoperative complications in laparoscopic group ,was lower than that in open group, the difference ,was statistically significant （P〈0.05）. Conclusion The three-hole laparoscopic RP has less trauma, lower morbidity of postoperative complications, and can achieve the same curative effect as open treatment, and it is worthy of clinical application.

关 键 词：前列腺切除术 前列腺肿瘤 腹腔镜 外科手术 治疗 

分 类 号：R737.25[医药卫生—肿瘤]