应重视可治性神经肌肉病的早期诊断与治疗  

The importance of early diagnosis and treatment in treatable neuromuscular diseases

作　　者：张成[1] 朱瑜龄[1] ZHANG Cheng;ZHU Yu-ling(Department of Neurology,the First Affiliated Hospital,Sun Yat-sen University,Guangzhou 510080,Guangdong,China)

机构地区：[1]中山大学附属第一医院神经科,广州510080

出　　处：《中国现代神经疾病杂志》2018年第8期557-562,共6页Chinese Journal of Contemporary Neurology and Neurosurgery

基　　金：国家自然科学基金资助项目(项目编号:81271401);国家自然科学基金资助项目(项目编号:81471280);国家自然科学基金资助项目(项目编号:81771359);国家自然科学基金青年科学基金资助项目(项目编号:81601087);国家自然科学基金-广东省联合基金重点资助项目(项目编号:U1032004);广东省广州市2015年产学研专项项目(项目编号:1561000153)~~

摘　　要：神经肌肉病系病变累及周围神经、神经-肌肉接头和骨骼肌的疾病总称,共同特征为不同部位、不同程度的肌萎缩和肌无力。神经肌肉病种类繁多,多无特异性治疗方法,药物治疗不能阻止疾病进展,但仍有少部分神经肌肉病药物治疗有效,早期诊断和及时治疗可以显著延缓疾病进展和改善临床症状。本文主要概述可治性神经肌肉病的临床特点、诊断要点和治疗方法,以供神经科同道参考。Neuromuscular diseases represent a heterogeneous group of disorders involving peripheral nerves, neuromuscular junction （NMJ） and skeletal muscle. The most common symptoms are muscular weakness and amyotrophy in different body parts to varying degrees. Neuromuscular diseases have various types and most of those are lack of optimistic treatments. Pharmacological therapy usually cannot prevent the development of diseases, while a small group of neuromuscular diseases has a good therapeutic effect, and early diagnosis and timely treatment can delay disease progression and improve clinical symptoms. In this review, we will focus on the aspects of clinical features, diagnosis and specific treatment of treatable neuromuscular diseases.

关 键 词：神经肌肉疾病 综述 

分 类 号：R746[医药卫生—神经病学与精神病学]