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作 者:徐倩菲 徐宏伟[1] 戴彦苗 徐进康[1] XU Qian-fei;XU Hong-wei;DAI Yan-miao;XU Jin-kang(Kunshan Municipal Chinese Medicine Hospital,Jiangsu,Kunshan 215300,China)
出 处:《中国中西医结合消化杂志》2018年第7期609-612,共4页Chinese Journal of Integrated Traditional and Western Medicine on Digestion
摘 要:[目的]探讨联动成像技术(LCI)联合蓝激光放大内镜(BLI-ME)对胃黏膜肠上皮化生(IM)的诊断价值。[方法]共纳入100例因上消化道不适症状于2016年9月~2017年9月至我院内镜中心行胃镜检查的门诊患者。在全麻状态下,联合运用白光、LCI、BLI-ME模式行内镜观察,对不同模式下肠化生的特异性表现进行观察,观察完毕后取活检送病理检查,将内镜结果与病理诊断对照研究后行统计学分析。[结果]本研究共纳入100例研究对象,活检部位100处。各组对胃黏膜肠化生及胃黏膜活动性的判断均有统计学意义(P<0.05),对HP感染、炎性反应、萎缩的判断差异均无统计学意义(P>0.05)。LCI模式下观察区域呈淡紫色调与BLI-ME下见亮蓝嵴(LBC)同时存在,对胃黏膜肠化生诊断的敏感性、特异性、准确性均明显高于这两种观察特征分别单独存在。纳入病例中胃黏膜组织肠化程度以轻度为主。结合胃黏膜肠化生程度,LCI联合BLI-ME模式观察的病变阳性率最高,且在3组肠化生中分别占比最高。[结论]LCI联合BLI-ME模式诊断胃黏膜肠化生具有更高的诊断价值,可作为内镜下诊断胃黏膜肠上皮化生的方法。[Objective]To evaluate the diagnostic value of the linked color imaging(LCI)technique and blue laser magnifying endoscope(BLI-ME)for intestinal metaplasia(IM)of gastric mucosa.[Methods]This study contains a total of 100 out-patients who were checked up stomach in the endoscopy center of Kunshan Municipal Chinese Medicine Hospital from September 2016 to September 2017 due to upper gastrointestinal discomfort.Under general anesthesia,with the combination of white light,LCI,and BLI-ME models,the endoscopic observation was carried out.This research has observed the specific performances of Intestinal metaplasia(IM)in different modes.After the observation,a biopsy was taken to the department of pathology for inspection.The result of endoscopic observation and pathological inspection were made control study and were analyzed statistically.[Results]This research takes 100 out-patients as the research object,includes 100 biopsy parts.Each group has the statistical significance for the judgment of intestinal metaplasia and gastric mucosal activity(P0.05),and there is no statistical significance for the judgment of HP infection,inflammatory response and atrophy(P0.05).In the LCI model,the observation area presented a lavender which coexisted with the LBC in the BLI-M.In this situation,the sensitivity,specificity,and accuracy of the diagnosis of intestinal metaplasia(IM)of gastric mucosa were apparently higher than these two observed characteristics existed separately.The intestinal metaplasia(IM)of gastric mucosa was mainly in low-grade in these cases.Combined with the degree of intestinal metaplasia(IM)of gastric muco-sa,the positive rate of the lesion under the mode of LCIBLI-ME was the highest and took the highest proportion in the three groups of IM.[Conclusion]The combination mode of LCI and BLI-ME has a higher diagnostic value in the diagnosis of intestinal metaplasia(IM)of gastric mucosa and can be used as a measure to diagnose the intestinal metaplasia(IM)of gastric mucos
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