中成药致急慢性肝损伤的原因析要及防范  

Acute and chronic liver injury induced by Chinese patent medicine: Causes and precautions

作　　者：杨全军[1] 陈力 陈林林 郭澄[1] Quan-Jun Yang;Li Chen;Lin-Lin Chen;Cheng Guo(Department of Pharmacy,Sixth People’s Hospital Affiliated to Shanghai Jiaotong University Shanghai 200233,Chin)

机构地区：[1]上海交通大学附属第六人民医院药剂科,上海市200233

出　　处：《世界华人消化杂志》2018年第21期1273-1279,共7页World Chinese Journal of Digestology

基　　金：上海市临床药学重点专科建设项目;No.2017-373;上海卫计委重要薄弱学科建设项目;No.2016ZB0302-01~~

摘　　要：中成药因其临床疗效确切、服用方便而广受欢迎.但中药及其制剂引起的肝损伤是药物性肝损伤的重要原因之一.中成药的不规范应用和其复杂成分被怀疑是导致肝损伤的重要因素.目前针对中成药导致肝损伤的原因、类型和防范措施尚无系统研究.本文拟简要评述中成药导致急慢性肝损伤的原因和防范措施.Chinese patent medicines are popular due to their definite clinical efficacy, reliable quality, and good safety. However, Chinese medicine and its preparations are one of the main causes of drug induced liver damage. The hepatotoxic ingredients of Chinese patent medicines and the irrational application of Chinese patent medicines are the two main reasons for their hepatotoxicity. However, there are no systematic studies on the causes, types, and preventive measures for liver injury caused by Chinese patent medicines. This article aims to briefly review the causes and preventive measures of acute and chronic liver injury caused by Chinese patent medicines.

关 键 词：中成药 肝毒性 药物性肝损伤 合理用药 

分 类 号：R575[医药卫生—消化系统]