颈部动脉迂曲和认知功能障碍的相关性研究  

Study on the correlation of neck artery tortuosity and cognitive dysfunction

作　　者：殷亮[1] 李倩倩[1] 张丽娜[1] 钱伟东[1] 屈洪党[1] YIN Liang;LI Qian-qian;ZHANG Li-na;QIAN Wei-dong;QU Hong-dang(Department of Neurology,The First Affiliated Hospital of Bengbu Medical College,Benbu Anhui 233004,China)

机构地区：[1]蚌埠医学院第一附属医院神经内科,安徽蚌埠233004

出　　处：《蚌埠医学院学报》2018年第6期723-725,共3页Journal of Bengbu Medical College

基　　金：蚌埠医学院科技发展基金项目(BYKF1758);蚌埠市科技创新指导项目(20160302)

摘　　要：目的:探讨颈部动脉迂曲与认知功能障碍的发生及严重程度的关系。方法:收集行头颈部CT血管成像检查的病人162例。采用蒙特利尔智能量表评价病人认知功能;计算颈部动脉迂曲个数;分析颈部动脉迂曲与认知功能障碍严重程度的相关性。结果:相比较认知正常病人,认知功能障碍病人颈动脉迂曲的发生率明显增高(P<0.01)。多因素logistic回归分析显示,年龄和颈动脉迂曲是发生认知功能障碍的危险因素(P<0.01),而椎动脉迂曲与认知功能障碍无明显相关关系(P>0.05)。Pearson相关分析显示,颈动脉迂曲个数和认知功能障碍评分呈负相关关系(r=-0.618,P<0.05)。结论:颈动脉迂曲有可能是认知功能障碍的独立危险因素。Objective： To explore the relationship between neck artery tortuosity and cognitive dysfunction. Methods： One hundred and sixty-two patients detected by CT angiography of head and neck were selected. The cognitive function of patients was evaluated using the Montreal Intelligence Scale. The number of neck artery tortuosity was calculated. The relationship between neck artery tortuosity and cognitive dysfunction was analyzed. Results： Compared with normal people,the incidence rate of neck artery tortuosity was significantly higher in patients with cognitive dysfunction（ P〈0. 01）. Logistic regression analysis indicated that the age and neck artery tortuosity were the risk factors of cognitive dysfunction（ P〈0. 01）,but the vertebral artery tortuosity was unrelated to the cognitive dysfunction（ P〉0. 05）. The Pearson correlation analysis showed that the cognitive dysfunction score was negatively correlated with the neck artery tortuosity number（ r =-0. 618,P〈0. 05）. Conclusions： Neck artery tortuosity may be the independent risk factor of cognitive dysfunction.

关 键 词：颈部动脉迂曲 认知功能障碍 体层摄影术 X线计算机 

分 类 号：R741.02[医药卫生—神经病学与精神病学]