25G玻璃体切除术联合或不联合内界膜剥除术治疗严重增殖型糖尿病视网膜黄斑水肿的对比分析  

Comparative analysis of 25G vitrectomy combined with or without internal limiting membrane peeling for severe proliferative diabetic macular edema

作　　者：彭永奎 刘新玲 许英杰 PENG Yong-kui;LIU Xin-ling;XU Ying-fie(Aier Eye Hospital of Shijiazhuang,Shijiazhuang 050000,China)

机构地区：[1]石家庄爱尔眼科医院眼底病科,石家庄市050000 [2]保定爱尔眼科医院,河北省保定市071000

出　　处：《临床合理用药杂志》2018年第23期22-23,共2页Chinese Journal of Clinical Rational Drug Use

摘　　要：目的对比分析25G玻璃体切除术联合或不联合内界膜剥除术治疗严重增殖型糖尿病视网膜黄斑水肿的疗效。方法回顾性分析医院收治的32例(共38眼)严重增殖型糖尿病视网膜黄斑水肿患者的临床资料。根据术式不同分为观察组和对照组,每组19眼。对照组接受25G玻璃体切除术治疗,观察组在对照组基础上另行内界膜剥除术。比较2组术后6个月时最佳矫正视力、黄斑中心凹视网膜厚度及并发症发生情况。结果 2组患者术后最佳矫正视力均较术前有明显改善(P <0. 05),且观察组最佳矫正视力改善程度优于对照组(P <0. 05); 2组患者术后黄斑中心区视网膜厚度均较术前减少(P <0. 05),且观察组黄斑中心区视网膜厚度减少程度较对照组更为明显(P <0. 05)。结论 25G玻璃体切除术联合内界膜剥除术治疗增殖型糖尿病视网膜黄斑水肿,临床效果肯定,并发症发生风险较低,值得临床进一步研究与推广。Objective To compare and analyze the efficacy of 25G vitrectomy combined with or without internal limiting membrane peeling in the treatment of severe proliferative diabetic macular edema. Methods The clinical data of 32 patients （38 eyes） with severe proliferative diabetic macular edema were retrospectively analyzed. Patients were divided into observation group and control group according to different operative methods, 19 eyes in each group. The control group was treated with 25G vitrectomy, while the observation group was additionally treated with internal limiting membrane removal on the basis of the control group. The BCVA, MRT and complications were compared between the 2 groups at 6 months after operation. Results The postoperative BCVA of the 2 groups was significantly improved compared with that before operation （P 〈 0.05 ）, and the improvement degree of BCVA in the observation group was significantly better than that in the control group （ P 〈 0.05 ）. The MRT of the 2 groups decreased significantly compared with that before operation （ P 〈 0.05 ）, and the decrease of MRT in the observation group was more obvious than that in the control group （P 〈 0.05）. Conclusion The efficacy of 25 G vitrectomy combined with internal limiting membrane peeling for severe proliferative diabetic macular edema is worth affirming. And the risk of complications is low, which is worthy of further clinical research and promotion.

关 键 词：25G玻璃体切除术 内界膜剥除术 糖尿病视网膜黄斑水肿 

分 类 号：R779.6[医药卫生—眼科] R587.2[医药卫生—临床医学]