第3代双源CT肝脏灌注平均时态图像在肝癌诊断中的可行性  被引量:5

Feasibility study of mean temporal phase images calculated from perfusion CT datasets on the third-generation dual-source CT in the diagnosis of hepatocellular carcinoma

在线阅读下载全文

作  者:余鑫 郑兴菊[1,2] 王玉权 张小勇[1,2] 唐滢 张媛[1,2] 王荣品 YU Xin1,2, ZHENG Xingju1,2, WANG Yuquan1,2, ZHANG Xiaoyong1,2, TANG Ying1,2, ZHANG Yuan1, 2 WANG Rongpin1, 2(1. Department of Radiology, Guizhou Provincial People's Hospital, Guiyang 550002, P. R. China; 2. Key Laboratory of Intelligent Medical Imaging Analysis and Accurate Diagnosis, Guiyang 550002, P. R. Chin)

机构地区:[1]贵州省人民医院放射科,贵阳550002 [2]贵州省智能医学影像分析与精准诊断重点实验室,贵阳550002

出  处:《中国普外基础与临床杂志》2018年第8期997-1003,共7页Chinese Journal of Bases and Clinics In General Surgery

摘  要:目的探讨第3代双源CT肝脏灌注平均时态图像在原发性肝癌临床诊断中的可行性。方法回顾性收集贵州省人民医院2017年9月至2017年12月期间确诊为肝癌的患者22例,所有患者行CT灌注成像(CTP)检查,提取3~5期最佳动脉期/门静脉期图像进行融合重建,相应得到平均动脉期时态(mean temporal arterial,m TA)图像/平均门静脉期时态(mean temporal portal venous,m TPV)图像,并与常规动脉期/门静脉期图像进行比较。结果 (1)图像质量:CTP图像的肝脏(动脉期)、门静脉(动脉期)和肝脏(门静脉期)的图像噪声(SD)值均低于常规增强图像(P<0.05),CTP图像的主动脉(动脉期)、门静脉(动脉期)、主动脉(门静脉期)和门静脉(门静脉期)的信噪比(SNR)值均高于常规增强图像(P<0.05),CTP图像的主动脉(动脉期)的对比噪声比(CNR)值高于常规增强图像(P<0.05)。(2)图像质量主观评价:CTP图像的主观评分(包括图像噪声、图像锐利度及总体图像质量)均高于相应常规增强图像(P<0.05)。(3)诊断效能:CTP图像与常规增强图像均能显示所有的肝脏病灶,CTP图像对肝脏富血供和乏血供病灶的图像诊断质量均高于常规增强图像(P<0.05)。结论从肝脏CTP原始图像上提取融合得到的m TA/m TPV图像的图像质量能满足临床诊断要求。CTP成像可用于"一站式"成像检查,无需另加做常规动脉期及门静脉期检查,有很好的临床应用前景。Objective To explore the feasibility of mean temporal phase images calculated from perfusion CT datasets by using CT perfusion(CTP) of liver on the third-generation dual-source CT.Methods Twenty-two consecutive patients with suspected hepatocellular carcinoma were enrolled,we retrospectively compared objective and subjective image quality,leson detectability,and radiation dose between mean temporal arterial(m TA) and mean temporal portal venous(m TPV) images which calculated from perfusion CT datasets with conventional enhanced arterial and portal venous datasets.Results(1) Image quality:compared with the conventional enhancement image,the standard deviation(SD) values of CTP images on liver(arterial phase),portal vein(arterial phase),and liver(portal vein phase) were lower(P0.05);the signal-to-noise ratio(SNR) values of CTP images on aorta(arterial phase),portal vein(arterial phase),aorta(portal vein phase),and portal vein(portal vein phase) were all higher(P0.05),the contrast-to-noise ratio(CNR) value of CTP images on aorta(arterial phase) was higher(P0.05).(2) The subjective image quality:the subjective image quality scores of CTP images(m TA and m TPV images) were higher when compared to responding conventional enhanced arterial and portal venous datasets(P0.05).(3) The diagnostic efficiency:the CTP images and conventional enhancement images showed all the lesions,but the diagnostic efficiency images of CTP images was better than the conventional enhancement images,both on lesions of blood supply and lack of blood supply(P0.05).Conclusions The image quality of m TA and m TPV datasets calculated from CTP datasets are non-inferior when compared to conventional enhanced arterial and portal venous acquisitions in patients with suspected hepatic lesions.Thus,CTP could be used as a standalone imaging technique without additionally performed conventional arterial and portal venous CT acquisitions.

关 键 词:CT灌注 第3代双源CT 肝癌 

分 类 号:R730.44[医药卫生—肿瘤] R735.7[医药卫生—临床医学]

 

参考文献:

正在载入数据...

 

二级参考文献:

正在载入数据...

 

耦合文献:

正在载入数据...

 

引证文献:

正在载入数据...

 

二级引证文献:

正在载入数据...

 

同被引文献:

正在载入数据...

 

相关期刊文献:

正在载入数据...

相关的主题
相关的作者对象
相关的机构对象