云南宁蒗地区摩梭人重性抑郁障碍与恶劣心境的流行病学调查  

The epidemiological investigation of major depressive disorder and dysthymia in mosuo ethnic minority of Ninglang area, Yunnan province

作　　者：徐莉[1] 王嫱[2] 杨尽梅[2] 林媛媛 张海音 冯国华[1] 曾贤威 仲华 陈芳[2] 储南疆 元静[1] 张艳[1] 卫芋君 周芳[1] 杨建中[1] Xu Li, Wang Qiang, Yang Jinmei, Lin Yuanyuan, Zhang Haiyin, Feng Guohua, Zeng Xianwei, Zhong Hua, Chen Fang, Chu Nanjiang, Yuan Jing, Zhang Yan, Wei Yujun, Zhou Fang, Yang Jianzhong(Department of Psychiatry, The Second Affiliated Hospital of Kunming Medical University, Kunming 650101, China ; Medical Examination Center, Second People ＇s Hospital of Yunnan Province, Kunming 650101, Chin)

机构地区：[1]昆明医科大学第二附属医院精神科,昆明650101 [2]云南省第二人民医院体检中心,昆明650101

出　　处：《中华行为医学与脑科学杂志》2018年第8期758-762,共5页Chinese Journal of Behavioral Medicine and Brain Science

基　　金：国家自然科学基金项目（81660235）;云南省卫生计生委医学领军人才培养计划（L-201623）

摘　　要：目的 调查云南省宁蒗地区泸沽湖周边摩梭人重性抑郁障碍与恶劣心境的患病情况,为开展防治工作提供依据.方法 采取多阶段分层随机抽样的方法,采用DSM-5-TR轴I障碍定式临床检查病人版（SCID-I/P）进行诊断,包含抑郁障碍分类临床描述与诊断要点中的重性抑郁障碍、恶劣心境的诊断,使用定式检查问卷简明国际精神病访谈（the MINI-international neuropsychiatric interview,M.I.N.I.）量表,调查1 121名15岁及以上摩梭人的抑郁障碍患病情况.结果 摩梭人重性抑郁障碍的标准化时点患病率为1.74％,男、女性分别为1.69％（95％ CI=1.32％～2.15％）和1.77％（95％ CI=1.39％～2.15％）,男、女性患病率差异无统计学意义（x2=0.051,P＞0.05）;恶劣心境的标准化时点患病率为0.78％,男、女性分别为0.66％（95％ CI=0.54％～0.78％）和0.88％（95％ CI=0.74％～1.02％）,男、女性患病率差异无统计学意义（x2=1.232, P＞0.05）;重性抑郁障碍现患的标准化时点患病率以40～54岁组的最高,为1.48％ （95％CI=0.77％～2.18％）.结论 摩梭人抑郁障碍的患病率较低,重性抑郁障碍时点患病率在中年组最高.Objective To explore the prevalence of depressive disorder in the Mosuo ethnic minority in Ninglang district,Yunnan Province.Methods By stratified random sampling,1 121 Mosuo subjects aged 15 or above were selected and assessed by the MINI-international neuropsychiatric interview according to the Structured Clinical Interview for DSM-V-TR Axis I Disorders-Patient Edition for mental disorders.Results The standardized time-point prevalence of major depressive disorder in Mosuo nationality was 1.74%,and 1.69% （95 % CI =1.32%-2.15 %） in males and 1.77% （95 % CI =1.39%-2.15 %） in females.There was no statistically significant difference in the prevalence of major depressive disorder between males and females （x2 =0.051,P〉0.05）.The standardized time-point prevalence of dysthymic disorder in Mosuo nationality was 0.78%,and 0.66% （95% CI=0.54%-0.78%） in males and 0.88% （95% CI=0.74%-1.02%） in females （x2=1.232,P〉0.05）.Those aged 40-54 years old had the highest adjusted prevalence of depressive episodes（1.48% （95%CI=0.77%-2.18%））.Conclusion The prevalence of depressive disorder in Mosuo nationality is in a low level,and the middle-age Mosuo people has the highest time-point prevalence.

关 键 词：摩梭人 重性抑郁障碍 恶劣心境 流行病学调查 

分 类 号：R749.4[医药卫生—神经病学与精神病学]