干预措施对产前筛查高风险孕妇产前诊断依从性的影响  

Effect of intervention measures on compliance of prenatal diagnosis among high-risk pregnant women in prenatal screening

作　　者：付天明[1,2] 舒敏思 高春元 王兴碧[1,2] FU Tian-Ming;SHU Min-Si;GAO Chun-Yuan(Department of Gynecology and Obstetrics,Maternal and Child Health Care Hospital of Longquanyi District,Chengdu,Sichuan 610100,China)

机构地区：[1]成都市龙泉驿区妇幼保健院妇产科,四川成都610100 [2]成都市龙泉驿区产前筛查中心,四川成都610100

出　　处：《中国妇幼保健》2018年第16期3757-3759,共3页Maternal and Child Health Care of China

基　　金：成都市卫生局青年基金(2012008);成都市龙泉驿区科技局社会发展基金(2013);成都市龙泉驿区医学会科学技术带头人培养对象专项基金(2013-2016)

摘　　要：目的探讨干预措施对产前筛查高风险孕妇产前诊断依从性的影响,以指导后续工作的持续改进提供依据。方法分别对产前筛查干预措施实施前、后在成都市龙泉驿区产前筛查中心检测为产前筛查高风险的孕(产)妇进行问卷调查、电话随访、微信或社区随访,明确产前筛查高风险孕妇产前诊断依从性的确切数据,从而评价干预措施效果,为后续措施制定提供指导。结果 2011-2016年成都市龙泉驿区筛查高风险孕妇21-三体和18-三体综合征的产前诊断依从率分别为:干预措施实施前的2011-2012年50.00%,实施阶段的2013-2014年79.84%,实施后阶段的2015-2016年92.85%,干预措施实施前、后3个时间段产前诊断依从率差异有统计学意义(P<0.01)。2015-2016年开放性神经管缺陷产前系统彩超诊断率10.00%比2011-2012年的33.96%及2013-2014年的14.29%显著下降,差异有统计学意义(P<0.01)。结论干预措施提高了成都市龙泉驿区产前筛查高风险孕妇羊水穿刺产前诊断依从性,但由于产前超声诊断资源匮乏,系统彩超诊断呈现下滑趋势。有待进一步丰富干预措施的形式及内容,增加产前诊断机构设置,提高产前筛查高风险孕妇产前诊断依从率。Objective To explore the effect of intervention measures on compliance of prenatal diagnosis among high-risk pregnant women in prenatal screening,provide a basis for directing continuous improvement of subsequent work. Methods Questionnaire investigation,telephone follow-up,We Chat and community follow-up were performed among the high-risk pregnant women in prenatal screening before and after implementation of intervention measures of prenatal screening in Prenatal Screening Center of Longquanyi District. The exact data of compliance of prenatal diagnosis was confirmed,then the intervention effect was evaluated to provide guidance for subsequent measures. Results From 2011 to 2016,the compliance of prenatal diagnosis of trisomy 21 syndrome and trisomy 18 syndrome were 50. 00%（ 2011-2012,before implementation of intervention measures）,79. 84%（ 2013-2014,during implementation of intervention measures）,and 92. 85%（ 2015-2016,later phase of implementation of intervention measures）,respectively. There was statistically significant difference in the compliance of prenatal diagnosis among the three time periods（ P〈0. 01）. From 2015 to 2016,the diagnostic rate of neural tube defects by prenatal systematical ultrasonography was 10. 00%,which was statistically significantly lower than those during 2011-2012（ 33. 96%） and 2013-2014（ 14. 29%）（ P〈0. 01）. Conclusion Intervention measures improve compliance of prenatal diagnosis of among high-risk pregnant women in prenatal screening in Longquanyi District,Chengdu. The diagnostic rate of systematical ultrasonography showed a decreasing trend due to deficiency of resource of prenatal ultrasonic diagnosis. Prenatal diagnostic institutions should be increased to improve compliance of prenatal diagnosis.

关 键 词：产前筛查 产前诊断 依从性 

分 类 号：R173[医药卫生—妇幼卫生保健]