防石利胆汤联合腹腔镜下保胆取石术对胆囊结石疗效及对胆囊功能影响  

Clinical Observation on Effect of Fangshi Lidan Decoction Combined with Laparoscopic Gallbladder Preserving Lithotomy in Patients with Cholecystolithiasis

作　　者：朱建敬[1] 蒋国祯[1] 朱一平[2] 胡胜军[1] ZHU Jianjing;JIANG Guozhen;ZHU Yiping;HU Shengjun(Department of Hepatobiliary Surgery,Jinhua People＇ s Hospital,Jinhua 321000,Zhejiang,China;Sir Run Run Shaw Hospital Affiliated of Zhejiang University School of Medicine,Hangzhou 310016,Zhejiang,China)

机构地区：[1]金华市人民医院肝胆外科,浙江金华321000 [2]浙江大学医学院附属邵逸夫医院,浙江杭州310016

出　　处：《中华中医药学刊》2018年第8期2022-2025,共4页Chinese Archives of Traditional Chinese Medicine

基　　金：金华市社会发展重点项目(2015-3-014)

摘　　要：目的：探讨防石利胆汤联合腹腔镜下保胆取石术对胆囊结石患者临床疗效及对胆囊功能影响。方法：胆囊结石患者150例，按照随机数字表法分为A组50例、B组50例、c组50例。C组仅采用腹腔镜下保胆取石术治疗；A组于术后第4天开始服用防石利胆汤治疗，连续服用1个月；B组于术后3d口服消炎利胆片，连续服用1个月。比较3组术前、术后第4天、术后1个月、术后2个月、术后3个月及术后1年空腹胆囊壁厚度和胆囊容积、胆囊残余指数和胆囊排空率变化，及术后第4天、术后10d、术后20d、术后30d主要症状腹胀、胁痛、便秘评分变化。结果：A组术后1个月、2个月、3个月及1年空腹胆囊壁厚度低于同期B组和c组（P〈0．05）；A组术后1个月、2个月、3个月及1年胆囊残余指数低于同期B组和C组，而胆囊排空率高于同期B组和C组（P〈0．05）：A组术后10d、术后20d、术后30d腹胀、肋痛及便秘评分低于同期B组（P〈0．05）。结论：防石利胆汤联合腹腔镜下保胆取石术对胆囊结石患者临床疗效明显，且可改善胆囊功能，具有重要研究价值。Objective： To investigate the clinical effect of Fangshi Lidan Decoction combined with laparoseopie gall- bladder preserving lithotomy in patients with cholecystolitbiasis. Methods： 150 patients with cholecystolithiasis were ran- domly divided into A group 50 cases, B group 50 cases, C group 50 cases. C group only received laparoscopic gallblad- der stone removal treatment. A group received Paishi Decoction 4 d after operation, continuously for 1 month. B group af- ter oral anti - inflammatory tablets 3 d, continuously used for 1 month. The three groups were compared before and 3 d, 1, 2 and 3 months and 1 year after surgery. We measured the gallbladder wall thickness, residual gallbladder and gall- bladder emptying rate index changes of main symptoms 4 d, 10 d, 20 d and 30 d after operation, main symptoms of hypo- chondriac pain, abdominal distension, constipation score changes 4 d, 10 d, 20 d and 30 d after operation. Results： In A group 1,2 and 3 months and 1 year after operation, the fasting gallbladder wall thickness was lower than that in B group and C group at the same time（P 〈0. 05）. In A group 1,2 and 3 months and 1 year after operation,the residual gallblad- der index was lower than that in B group and C group at the same period and gallbladder emptying rate was higher than that of B group and C group （P 〈0. 05）. A group＇ s abdominal distension, pain and rib constipation score 10 d, 20 d, 30 d after operation were lower than those in B group （ P 〈 0. 05 ）. Conclusion ： The prevention and treatment of Fangshi Lidan Decoction combined with ]aparoscopic cholecystectomy is an effective method in the treatment of patients with cho- lecystolithiasis.

关 键 词：防石利胆汤 腹腔镜下保胆取石术 胆囊结石 疗效 胆囊功能 

分 类 号：R575.6[医药卫生—消化系统]