正常中老年人房角的3D-光学相干断层初步研究  

3D-optical coherence tomography of anterior chamber angle in normal eyes of the middle-aged and the elderly

作　　者：郑彪 彭红娟 黎思毅 柯毅 ZHENG Biao;PENG Hong-juan;LI Si-yi;KE Yi(Department of Ophthalmology;Department of Thyroid-Mammary Surgery,the Affiliated Hospital of Guangdong Medical University,Zhanjiang 524001,China)

机构地区：[1]广东医科大学附属医院眼科,广东湛江524001 [2]广东医科大学附属医院甲状腺乳腺外科,广东湛江524001

出　　处：《广东医科大学学报》2018年第3期260-263,共4页Journal of Guangdong Medical University

摘　　要：目的探讨正常中老年人房角结构的直观、客观改变,为今后进一步研究原发性闭角型青光眼(PACG)提供参考。方法选取正常人84例84只眼为研究对象,应用光学相干断层扫描仪3D-OCT扫描房角,观察房角图像特征,并以房角开放距离(SL-AOD)及小梁虹膜间面积(定量评估房角。结果SL-TISA)schwalbe线(SL)的3D-OCT发现率占92.9%(78/84),巩膜突(SS)占47.6%(40/84),两者比较差异有统计学意义(P<0.05);女性的SL-AOD及SL-TISA均明显小于男性(P<0.05);SL-AOD与SL-TISA在40~69岁之间随着年龄的增加而变小;但在70~79岁的数值只比40~49岁的小(P<0.05),与50~59、60~69岁年龄阶段相比差异无统计学意义(P>0.05)。结论 3D-OCT能清晰显示小梁网的形态及SL线,女性的房角明显窄于男性,在40~69岁之间,房角随着年龄的增加而变窄,但在70岁以后房角变宽,可能为临床和研究PACG提供新思路。Objective To study the visual and objective changes in anterior chamber angle structure of normal eyes of the middle-aged and the elderly and provide reference for the further study on primary angle closure glaucoma（PACG）. Methods A total o f 84 normal eyes of 84 middle-aged and elderly persons in our hospital from January 2013 to October 2014 were chosen as the objects. 3 D-OCT was used to scan the anterior chamber angle and observe the imaging features of anterior chamber angle. Schwalbe line-angle opening distance（SL-AOD） and Schwalbe line trabeculareiris space area（SL-TISA） was used for quantitative evaluation of anterior chamber angle. Results A total of 78 cases had the schwalbe line（SL） identified in 3 D-OCT, accounting for 92.9%（78/84）, and a total of 40 cases had the scleral spur（SS） identified in 3 D-OCT, accounting for 47.6%（40/84）, and the difference was statistically significant（P〈0.05）; Females had the SL-AOD and SL-TISA significantly less than males（P〈0.05）; the SL-AOD and SL-TISA diminished with the increase of age within an age range of 40-69 years; but the value at the age of 70-79 years was less than that at the age of 40-49 years（P〈0.05）, but had no significant difference compared with that at the age of 50-59 years, or at the age of 60-69 years（P〈0.05）. Conclusion 3 D-OCT can clearly show the shape of the trabecular meshwork and the SL line. The anterior chamber angle of females was narrower than that of males. The anterior chamber angle becomes narrower with the increase of age within the age range of 40-70 years, but become broadened after the age of 70 years, which may possibly provide a new idea for the clinical practice and study on PACG.

关 键 词：原发性闭角型青光眼 房角 光学相关断层扫描 schwalbe线 

分 类 号：R775[医药卫生—眼科]