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机构地区:[1]解放军145医院病理科 [2]第三军医大学附一院病理科
出 处:《中国肿瘤临床》1991年第2期96-98,共3页Chinese Journal of Clinical Oncology
摘 要:本文对5例烧伤疤痕癌从组织结构和细胞分化方面进行了较详细的观察,看到假上皮瘤性增生向癌的移行过程,癌组织从病变浅层到深层由高分化向中分化、低分化的演变过程。对鳞癌的组织学分级提出以Ⅰ、Ⅱ、Ⅲ级为基础并分别以a、b、c标出其分化程度。对假上皮瘤性增生与高分化鳞癌的鉴别进行了探讨,并对疤痕癌与预后的关系进行简要讨论,同意Engler认为要比一般皮肤癌更具有恶性度的观点。Five cases of carcinoma developed in burn scars were studied histGlogieally. The transition from pseudo-epitheliomatous proliferation to carcinoma was noted in all. The differentiation of neoplastic cells usually was poorer in the deeper layers than those in the superficial area. For squamous cell carcinoma, in addition to Ⅰ, Ⅱ, Ⅲ grading, subsets such as a, b, c were used to mark the degree of differentiation. Lesion designated as pseudoepitheliomatous proliferation should be carefully distinguished from a well-differentiated squamous cell carcinoma. The authors emphasize the need to consider these lesions as highly malignant since the prognosis are usually more grave than those of the ordinary skin cancers.
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