无功能性阑尾神经内分泌肿瘤的临床病理特点及预后研究  

The Clinicopathologic Characters and Prognosis of Nonfunctioning Neuroendocrine Tumors Appendix

作　　者：卢晓玉 LU Xiaoyu(He＇nan Cancer Hospital,Zhengzhou,45000)

机构地区：[1]河南省肿瘤医院,450000

出　　处：《实用癌症杂志》2018年第9期1502-1504,共3页The Practical Journal of Cancer

基　　金：国家自然科学基金资助项目(编号:30872464)

摘　　要：目的总结无功能性阑尾神经内分泌肿瘤的临床病理特点,分析其与预后的关系。方法回顾性分析18例无功能性阑尾神经内分泌肿瘤患者的临床病理特点。结果无功能性阑尾神经内分泌肿瘤的病理分级、病理学特点不同,其预后也不相同。18例患者中,无功能性阑尾神经内分泌肿瘤G_1级12例,G_2级5例,G_3级或神经内分泌癌1例。G_1、G_2患者5年生存率达100%;1例G_3级或神经内分泌癌患者术后1年死亡。结论无功能性阑尾神经内分泌肿瘤病理分级与预后关系密切,肿瘤远处转移及细胞分化程度决定是否可以进行根治性手术切除,这是影响预后的关键。Objective To investigate the clinicopathological features and prognosis of the nonfunctioning neuroendocrine appendix tumors. Methods The clinicopathological data of 18 patients with nonfunctional neuroendocrine appendix tumor were analyzed retrospectively. Results The pathological features and prognosis of neuroendocrine appendix tumor were different. Incidences of nonfunctional neuroendocrine appendix tumor G1 were 12 cases,G2 were 5 cases,G3 or neuroendocrine carcinoma was 1 case. 5-year survival rate in G1 and G2 were 100%. 1 case of G3 or neuroendocrine carcinoma was dead 1 year after operation.Conclusion Nonfunctional neuroendocrine appendix tumor pathological grading and clinical staging are related to prognosis closely. Radical resection depends on the tumor distant metastases and cell differentiation,which is the key to the prognosis.

关 键 词：阑尾 神经内分泌肿瘤 病理学 

分 类 号：R730.264[医药卫生—肿瘤]