低水平激光治疗促进正畸牙齿移动的研究进展  

Research progress of effect of low-level laser therapy during orthodontic tooth movement

作　　者：王晓琨[1] 赵忠琪 彭慧敏[1] 王小晋 梁家迪 刘畅[1,2] WANG Xiaokun;ZHAO Zhongqi;PENG Huimin;WANG Xiaojin;LIANG Jiadi;LIU Chang(Department of Orthodontic,Stomatology Hospital,Jilin University,Changchun 130021,China)

机构地区：[1]吉林大学口腔医院正畸科,吉林长春130021 [2]广州医科大学附属口腔医院·广州口腔病研究所·口腔医学重点实验室,广东广州510140

出　　处：《口腔医学》2018年第8期756-760,共5页Stomatology

基　　金：广东省教育厅项目(B16036078)

摘　　要：低水平激光治疗(low-level laser therapy,LLLT)是被FDA批准应用于临床的一种安全、无创的治疗方法,可通过使用600~1 000 nm的单色可见红光或近红外光对细胞和组织产生光生物刺激作用。目前,LLLT广泛应用于促进伤口愈合,缓解疼痛,减少炎症,再生医学等领域。现有研究认为,LLLT的分子和细胞机制主要与线粒体电子呼吸链有关,通过促进ATP的生成,调节细胞新陈代谢。大量研究表明,LLLT可通过促进牙周膜和牙槽骨的生理性改建,加速牙齿移动,进而缩短正畸治疗时间。由于LLLT的光生物刺激作用、非侵入性方式等特点使其在加速正畸牙齿移动方面有广泛的应用前景。该文就LLLT的作用机制,生物学效应及对正畸治疗中牙齿移动的促进作用进行探讨。Low-level laser therapy（ LLLT） is a safe,noninvasive technology that is approved by the FDA for clinical use. It can produce photobiostimulate on cells and tissues by using 600-1000 nm monochromatic red or near-infrared light. At present,LLLT has been widely applied to promoting the wound healing,relieving pain,reducing inflammation and regenerative medicine et al. It is believed that the molecular and cellular mechanisms of LLLT are mainly related to the respiratory chain of mitochondrion. In this way,mitochondrion are responsible for the cellular metabolism by promoting the formation of ATP. A large number of studies have shown that LLLT can reduce the orthodontic treatment duration and accelerate tooth movement by promoting the physiological alteration of periodontal ligament and alveolar. Because of the photobiostimulating and noninvasive way,LLLT has wide application prospect in accelerating orthodontic tooth movement. This review will cover the mechanism of LLLT,biological effects and its positive effect on orthodontic tooth movement.

关 键 词：低水平激光治疗 光生物调节作用 正畸牙齿移动 细胞色素氧化酶C 

分 类 号：R783.5[医药卫生—口腔医学]