佛山市高明区人民医院2014-2016年度新生儿先天性畸形分析  

Analysis of congenital malformation of newborn in People's Hospital of Gaoming District,Foshan City in 2014-2016

作　　者：罗玲云[1] 严美洁 肖厚兰[1] 杜佩珍[1] 刘淑霞[1] LUO Ling-yun;YAN Mei-jie;XIAO Hou-lan;DU Pei-zhen;LIU Shu-xia(Gaoming District People＇s Hospital,FoshanCity,Guangdong528500,China)

机构地区：[1]佛山市高明区人民医院,广东佛山528500

出　　处：《中国优生与遗传杂志》2018年第7期76-78,共3页Chinese Journal of Birth Health & Heredity

摘　　要：目的回顾性分析高明区人民医院2014-2016年度新生儿先天性畸形发生情况,并探讨其相关影响因素。方法纳入2014-2016年度在高明区人民医院妇产科分娩的20 481例围产儿资料进行回顾性分析,统计这一期间先天性畸形检出率;727例已确诊先天畸形儿作为观察组,700例正常新生儿作为对照组,分析先天性畸形相关影响因素。结果 2014~2016年度总共检出727例先天性畸形儿,检出率3.55%,尤以肢体畸形(1.27%)、先天性心脏病(0.68%)的检出率最高,其中地中海贫血检出率有逐年上升趋势;因素分析结果显示,低出生体重、产母有既往病史、文化程度低、遗传病史、产母有妊娠合并症、孕期服用抗生素药物、孕期接触农药、父亲慢性病是先天性畸形高危因素,而孕期定期产检是先天性畸形的保护因素。结论该地区先天性畸形类型以肢体畸形、先天性心脏病为多,地中海贫血发生率有上升趋势;应加强孕早期健康知识宣导力度,让产妇意识到产检的重要性,并提高自我保护意识,降低该地区新生儿先天性畸形发生率。Objective：To retrospectively analyze the incidence of congenital malformations in the people＇s Hospital of Gaoming District in 2014-2016,and to explore the related factors. Methods：A total of 2014-2016 were retrospectively analyzed in Gaoming District People＇s Hospital of gynaecology and obstetrics childbirth 20481 cases of perinatal data statistics,during this period the congenital malformation rate;727 cases of congenital malformations in the observation group,700 cases of normal newborns as control group,analysis of relevant factors of congenital malformation. Results：A total of 2014-2016 detection of congenital malformation in 727 cases,the detection rate of 3.55%,especially in limb malformations（1.27%）,congenital heart disease（0.68%）the highest detection rate,which increased year by year in Mediterranean anemia detection rate;factor analysis results showed that,low birth weight,maternal medical history and culture degree low genetic history,maternal complications during pregnancy,pregnancy taking antibiotics drugs during pregnancy,exposure to pesticides,father of chronic disease is a congenital malformation of the risk factors and pregnancy,regular prenatal congenital abnormalities of the protective factors. Conclusion：The type of congenital malformation in the region with limb deformities,congenital heart disease,the incidence of thalassemia increased;early pregnancy should strengthen health knowledge propaganda efforts to make women aware of the importance of production inspection,and to raise awareness of self-protection,to reduce the area of neonatal congenital malformation incidence.

关 键 词：新生儿 先天性畸形 影响因素 回归分析 

分 类 号：R722.1[医药卫生—儿科]