乳酸酸中毒的临床诊疗分析  

Analysis of clinical diagnosis and treatment of lactic acidosis

作　　者：廉宏伟[1] 田兆兴[1] 刘桂花[1] Lian Hongwei;Tian Zhaoxing;Liu Guihua(Peking University Third Hospital,Beijing 100191,China)

机构地区：[1]北京大学第三医院,100191

出　　处：《中国中西医结合急救杂志》2018年第4期446-448,共3页Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care

基　　金：国家自然科学基金（81172745）

摘　　要：乳酸是葡萄糖无氧代谢的最终产物，正常人体内存在乳酸循环，维持血乳酸水平在正常范围。多种原因导致呼吸循环障碍可使乳酸水平升高，血乳酸水平的异常升高是疾病严重程度的重要指标。本文就脓毒症、器官衰竭、休克等危重症与乳酸水平升高的相关性以及血液净化特别是持续性高容量血液滤过清除乳酸的治疗价值进行综述如下。Lactic acid is the final product of glucose anaerobic metabolism. There exists a lactic acid cycle in the normal human body which can maintain the level of blood lactate in the normal range. Many causes leading to respiratory and circulatory impairment may result in abnormal elevation of the level of blood lactic acid that is an important indicator of the severity of the disease. In this article, the clinical studies on the relationships between elevation of blood lactic acid level and severe diseases, such as sepsis, organ failure and shock, and the therapeutic value of using blood purification, especially the persistent high-throughput blood purification to eliminate the excessive lactic acid were reported.

关 键 词：乳酸 乳酸酸中毒 持续性高容量血液净化 

分 类 号：R977.15[医药卫生—药品]