香砂六君子汤联合针灸治疗胃癌术后胃动力不足的临床疗效  

Clinical Effect of Xiangsha Liujunzi Soup Combined with Acupuncture in the Treatment of Patients with Gastric Cancer after Surgery and Lack of Gastric Motility

作　　者：杨格娟[1] 庞瑞[1] 孙永强[1] 谢丹[1] 马艳[1] YANG Gejuan;PANG Rui;SUN Yongqiang;XIE Dan;MA Yah(Chinese and Western Medicine Department,Tumor Hospital Affiliated to Xinjiang Medical University,Urumqi,Xinjiang,830001,China)

机构地区：[1]新疆医科大学附属肿瘤医院中西医科,新疆乌鲁木齐830001

出　　处：《肿瘤药学》2018年第4期639-643,共5页Anti-Tumor Pharmacy

基　　金：新疆医科大学科研创新基金项目(XYDCX201552)

摘　　要：目的探讨香砂六君子汤联合针灸治疗胃癌术后胃动力不足的临床疗效。方法选取我院收治的61例胃癌术后胃动力不足患者为研究对象,根据硬币投掷法随机分为对照组(30例)和研究组(31例)。对照组患者口服香砂六君子汤治疗,研究组患者在对照组的基础上联合针灸治疗。比较两组患者的临床疗效、治疗前后中医证候评分、血清胃动素及胃泌素水平、胃动力学指标变化及治疗后胃肠功能指标。结果研究组治疗总有效率明显高于对照组(P<0.05);治疗后研究组患者肠鸣音恢复时间、肛门排气时间及排便时间均显著短于对照组,血清MTL、Gas水平显著高于对照组,差异均有统计学意义(P<0.05);治疗前两组患者中医证候评分及胃动力学相关指标比较无明显差异(P>0.05),治疗后均明显改善,且研究组显著优于对照组(P<0.05)。结论香砂六君子汤联合针灸可有效改善胃癌术后胃动力不足患者的临床症状,提高胃动力,临床疗效显著,值得推广应用。Objective To explore on the clinical efficacy of Xiangsha Liujunzi soup combined with acupuncture in the treatment of pa- tients with gastric cancer after surgery and lack of gastric motility. Methods 61 patients with gastric cancer after surgery and lack of gastric motility were selected as the subjects. According to the coin throwing method, all patients were divided into control group （30 eases） and study group （3 leases）. The control group patients were treated with Xiangsha Liujunzi soup, while the study group had acupuncture treatment on the basis of control group. The clinical effect was compared between the two groups, as well as the TCM syndrome scores, the changes of serum motilin and gastrin levels, the changes of gastric motility indexes before and after treatment, and the changes of gastrointestinal rune- tion indexes after treatment. Results The total effective rate in the study group was obviously higher than in the control group （P 〈 0.05）. After treatment, the recovery time of bowel sounds, anal exhaust time and defecation time in study group were significantly shorter than in control group. The serum MTL and Gas levels were significantly higher in study group than in control group （P 〈 0.05）. Before treatment, there were no significant differences in TCM syndrome score and gastric dynamics index between the two groups （P 〉 0.05）. After treatment, the TCM syndrome score and gastric dynamics index were improved in both groups, and improved much greater in the study group than in the control group （P 〈 0.05）. Conclusions Xiangsha Liujunzi soup combined with acupuncture had good clinical effect. It could improve clinical symp- toms of patients and increase gastric motility. It is worth to promote in the treatment of patients with gastric cancer after surgery and lack of gastric motility.

关 键 词：香砂六君子汤 针灸 胃癌术后 胃动力不足 胃动素 胃泌素 

分 类 号：R735.2[医药卫生—肿瘤]