肺磨玻璃结节适应性统计迭代重建技术低常规剂量CT检查的应用研究  

Evaluation in clinical application of adaptive statistical iterative reconstruction low-dose CT examination in ground-glass opacity

作　　者：张秀明[1] 白晨光[1] 乔伟[1] 李康[1] 沈文荣[1] 

机构地区：[1]江苏省肿瘤医院CT与MRI室,江苏南京210009

出　　处：《中国肿瘤外科杂志》2018年第4期217-220,共4页Chinese Journal of Surgical Oncology

基　　金：江苏省卫生计生委科研项目(H201509);江苏省肿瘤医院青年科研项目(ZM201504)

摘　　要：目的评估适应性统计迭代重建(ASIR)低常规剂量与常规剂量CT检查在肺磨玻璃结节显示能力、图像质量及辐射剂量方面的差异性。方法 510名体检人群中,低常规剂量CT扫描发现肺磨玻璃结节患者31例,3~6个月复查常规剂量CT,观察两种检查方法图像在病灶噪声、肺小结节数量和形态、瘤-肺界面征(清晰度、分叶、毛刺)、结节内部特征(空泡征或蜂窝征、支气管狭窄或中断)和结节周围情况(血管集束征、胸膜凹陷征)以及辐射剂量方面差异性。结果低常规剂量的CT剂量加权指数(CTDIvol)为(3.16~3.6)m Gy,常规剂量扫描CTDIvol为(12.88~24.44)m Gy,低常规剂量组放射线辐射剂量低于常规检查组;低常规剂量组图像颗粒增粗,噪声增大,以纵隔窗较明显,肺窗肺尖处稍明显,病灶内部噪声值为47~265 Hu,而常规剂量扫描图像病灶内部噪声值为14.0~99.4 Hu,低于低常规剂量检查组(P<0.05)。两种检查在显示病灶数量、瘤-肺界面征、结节内部特征及周围情况方面,差异无统计学意义(P>0.05)。结论肺磨玻璃结节ASIR低常规剂量扫描可降低扫描剂量,虽病灶噪声增加、图像质量有一定程度下降,但不影响磨玻璃结节的检出及征象分析,可用于体检及磨玻璃结节的随访。Objective To compare ability for display, radiation dose and image quality on low-dose CT images reconstructed with adaptive statistical iterative reconstruction （ASIR） and conventional dose CT images. Methods： Among the 510 asymptomatic volunteers, 31 cases were found with ground-glass opacity （GGO） by low-dose CT examination, reviewed by conventional CT examination after 3-6 months. Compared radiation dose and lesions nose with two examinations, and analyzed the display of number and signs of GGO, including lobulation, speculation, cavitation, bronchus sign, and pleural indentation. Results： The CT dose index volume（CTDIvol） of low-dose CT were （3.16-3.6） mGy, and that of the conventional CT were （12.88-24.44） mGy. low-dose CT examination reconstructed with ASIR greatly reduced CT dose index volume （CTDIvol） compared with conventional CT examination; but low-dose CT increased lesions nose, especially on mediastinal window, apex pulmonis on lung window was a little obvious, the noise inside the lesion were 47-265Hu. But the noise of conventional CT inside the lesion were 14-99.4Hu, lower than the low-dose CT （P〈0.05）. Display the number and the sign of GGO inside or periphery, had no different between two examinations （P〉0.05）. Conclusion： Low-dose CT examination reconstructed with ASIR lowers radiation dose, increases lesion nose, but dose not affect the display of signs of GGO. It may be appropriate on healthful examination and following up GGO.

关 键 词：磨玻璃结节 低常规剂量 CT剂量指数 适应性统计迭代算法 

分 类 号：R734.2[医药卫生—肿瘤]