依托咪酯与丙泊酚对全麻患者血流动力学的影响  

The Effect of Etomidate and Propofol on Hemodynamics in Patients Undergoing General Anesthesia

作　　者：邓长流[1] 

机构地区：[1]重庆市第九人民医院麻醉科,重庆400700

出　　处：《中国继续医学教育》2018年第26期87-88,共2页China Continuing Medical Education

摘　　要：目的研究在全身麻醉手术患者中应用依托咪酯联合丙泊酚麻醉的效果。方法将2016年9月—2017年9月纳入的68例全身麻醉手术患者作为研究对象。采用随机数字表法,将其分为两组。参照组行托咪酯麻醉,实验组行依托咪酯联合丙泊酚麻醉,观察参照组和实验组全身麻醉手术患者的T_2时刻的MAP、HR以及不良反应发生率。结果 T_2时,实验组患者MAP指标为(130.21±2.32)mm Hg,HR为(75.32±3.33)次/min以及不良反应发生率为2.94%,对比参照组的(120.21±3.36)mm Hg、(72.32±4.21)次/min、20.59%,差异均具有统计学意义(P<0.05)。结论将依托咪酯联合丙泊酚麻醉应用在全身麻醉手术患者中展现更优异的作用,可显著降低不良反应,改善患者各项指标,提升麻醉效果。Objective To study the effect of etomidate combined with propofol anesthesia in patients undergoing general anesthesia. Methods 68 patients with general anesthesia from September 2016 to September 2017 were selected as the study objects and they were divided into groups with random digital table. The reference group was treated with imidolone. The experimental group received etomidate combined with propofol anesthesia. The incidence of MAP, HR and adverse reactions at T2 were observed in the control group and the experimental group. Results At T2, the MAP index was （130.21±2.32） mmHg, HR was （75.32±3.33） times/min, and the incidence of adverse reactions was 2.94%. Compared with the control group of （120.21±3.36） mmHg, （72.32±4.21） times/min, 20.59%, the diference was statistically significant （P 〈 0.05）. Conclusion The application of etomidate combined with propofol anesthesia in patients undergoing general anesthesia surgery shows a more excellent role, can signifcantly reduce adverse reactions, improve the patient＇s indicators, improve anesthesia efect.

关 键 词：依托咪酯 丙泊酚 全身麻醉手术 MAP HR 不良反应 

分 类 号：R614[医药卫生—麻醉学]