^(18)F-FDG PET/CT在乳腺癌诊断和术前分期评估中的价值研究  

Value of ^(18)F-FDG PET/CT in the Diagnosis and Preoperative Staging of Breast Cancer

作　　者：彭雪强 任谊 魏庆忠[1] 王钢[1] 苏超云[1] 郭雯 PENG Xue-qiang;REN Yi;WEI Qing-zhong(Department of General Surgery,Beijing Aerospace Hospital,Beijing 100076,China)

机构地区：[1]北京航天总医院普外科,北京100076

出　　处：《中国CT和MRI杂志》2018年第9期41-43,共3页Chinese Journal of CT and MRI

基　　金：北京市科技计划项目(Z141107006614010)

摘　　要：目的研究^(18)F-脱氧葡萄糖(^(18)FFDG)PET/CT在乳腺癌诊断和术前分期评估中的价值。方法将我院收治的69例疑似乳腺癌患者作为研究对象,均于术前进行^(18)F-FDGPET/CT检查,以术后病理结果为标准,分析^(18)F-FDGPET/CT对乳腺癌诊断的信效度及与病理结果诊断一致性,并分析^(18)F-FDGPET/CT对术前分期信效度。结果69例患者术后病理结果显示为乳腺癌者67例,^(18)F-FDG PET/CT检查结果显示SUV阳性者65例,阴性者4例,^(18)F-FDGPET/CT乳腺癌诊断诊断灵敏度为97.01%,特异度为100.00%,准确度为97.10%,与病理结果诊断一致性较好(κ=0.896)。^(18)FFDG PET/CT检查确诊为乳腺癌的65例患者中,术后病理结果显示I期者6例,Ⅱ期者35例,Ⅲ期者8例,IV期者16例;^(18)FFDG PET/CT检查显示I期者7例,Ⅱ期者32例,Ⅲ期者11例,IV期者15例;^(18)F-FDG PET/CT检查对乳腺癌术前分期诊断总准确度为89.23%。结论 ^(18)F-FDGPET/CT乳腺癌诊断准确性较高,能较好评估术前肿瘤分期。Objective To study the value of ^18F-FDG PET/CT in diagnosis and preoperative staging assessment of breast cancer. Methods A total of 69 cases of patients with suspected breast cancer treated in our hospital were selected for the study and were given ^18F-FDG PET/CT before operation. The postoperative pathological results were used as criteria to analyze the reliability and validity of ^18F-FDG PET/CT and its consistency with pathological diagnosis in the diagnosis of breast cancer and to analyze the reliability and validity of ^18F-FDG PET/CT to preoperative staging. Results The postoperative pathological results of 69 cases showed there were 67 cases of breast cancer, and the results of ^18F-FDG PET/CT showed that 65 cases were SUV positive and 4 cases were negative, and the diagnostic sensitivity, specificity and accuracy of ^18F-FDG PET/CT were 97.01%, 100% and 97.10% in the diagnosis of breast cancer, and its consistency with pathological diagnosis was better （κ=0.896）. Among 65 cases diagnosed with breast cancer by ^18F-FDG PET/CT, postoperative pathological results showed that there were 6 cases in I stage, 35 cases in II stage, 8 in III stage and 16 in IV stage. ^18F-FDG PET/CT showed that there were 7 cases in I stage, 32 cases in II stage, 11 in III stage and 15 in IV stage. The total accuracy of ^18F-FDG PET/CT was 89.23% in the diagnosis of preoperative staging of breast cancer. Conclusion ^18F-FDG PET/CT has high diagnostic accuracy in breast cancer, and can better evaluate preoperative tumor staging.

关 键 词：^18F-FDGPET/CT 乳腺癌 诊断 术前分期 

分 类 号：R737.9[医药卫生—肿瘤]