抗精神病药物联合无抽搐电休克治疗难治性精神分裂症87例的疗效分析  

Efficacy analysis of antipsychotic drugs combined with modified electroconvulsive therapy in the treatment of 87 patients with refractory schizophrenia

作　　者：崔文辉[1] CUI Wen-hui(Shenyang Mental Health Center,Shenyaag 110168,China)

机构地区：[1]沈阳市精神卫生中心,110168

出　　处：《中国实用医药》2018年第24期86-87,共2页China Practical Medicine

基　　金：沈阳市科学技术计划项目重点实验室专项(项目编号:F16-097-1-00)

摘　　要：目的探讨抗精神病药物联合无抽搐电休克(MECT)治疗难治性精神分裂症的疗效。方法 174例难治性精神分裂症患者,随机分为对照组和观察组,每组87例。对照组患者采用抗精神病药物治疗,观察组患者在对照组基础上采用无抽搐电休克治疗,比较两组患者的治疗效果。结果观察组总有效率为96.55%,对照组总有效率为87.36%,观察组患者总有效率高于对照组,差异具有统计学意义(P<0.05)。结论抗精神病药物联合无抽搐电休克治疗难治性精神分裂症疗效显著,值得在临床上应用推广。Objective To investigate the efficacy of antipsychoticsdrugs combined with modified electroconvulsive therapy （MECT） in the treatment of refractory schizophrenia. Methods A total of 174 patients with refractory schizophrenia were randomly divided into control group and observation group, 87 cases in each group. Patients in the control group were treated with antipsychotic drugs, and patients in the observation group were treated with modified electroconvulsive therapy on the basis of the control group. The treatment effect of the two groups was compared. Results The total effective rate of the observation group was 96.55%, the total effective rate of-the control group was 87.36%, the total effective rate of the observation group was significantly higher than that of the control group, the difference was statistically significant （P〈0.05）. Conclusion The efficacy of antipsychotic drugs combined with modified electroconvulsive therapy in the treatment of refractory schizophrenia is significant, it is worthy of clinical application and promotion.

关 键 词：抗精神病药物 无抽搐电休克 难治性精神分裂症 疗效 

分 类 号：R749.3[医药卫生—神经病学与精神病学]