3D与2D腹腔镜下经腹膜外前列腺癌根治术疗效与安全性比较的Meta分析  

Comparison of efficacy and safety between using 3D and 2D extraperitoneal laparoscopic technique in radical prostatectomy:a meta-analysis

作　　者：范宁[1] 祁萍[2] 张丽秀[3] 桂惠明[1] 丁辉[1] 宁忠运[1] 王志平[1] FAN Ning;QI Ping;ZHANG Lixiu;GUI Huiming;DING Hui;NING Zhongyun;WANG Zhiping(Department of Urology/Key Laboratory for Urological Diseases of Gansu Province/Clinical Center for Nephro-Urology of Gansu Province,Second Hospital of Lanzhou University,Lanzhou,730030,China;Department of Clinical Laboratory,Second Hospital of Lanzhou Universlty;Department of Clinical Laboratory Center,Gansu Provincial Maternity and Child-Care Hospital)

机构地区：[1]兰州大学第二医院泌尿外科甘肃省泌尿系统疾病研究重点实验室甘肃省泌尿系统疾病临床医学中心,兰州730030 [2]兰州大学第二医院检验科 [3]甘肃省妇幼保健院临床检验中心

出　　处：《临床泌尿外科杂志》2018年第8期633-637,645,共6页Journal of Clinical Urology

基　　金：甘肃省自然科学基金(编号1606RJZA044)

摘　　要：目的:使用Meta分析比较3D与2D腹腔镜下经腹膜外前列腺癌根治术的疗效与安全性。方法:检索各大数据库相关文献,由2名独立文献分析员进行质量评价及数据提取,利用Revman 5.3软件进行分析。结果:共纳入9篇文献,共705例患者。Meta分析结果显示:与2D腹腔镜比较,3D腹腔镜下经腹膜外前列腺癌根治术可以缩短手术时间(MD=-34.74,95%CI:-49.01^-20.46,P<0.000 01)、减少术中出血(MD=-48.53,95%CI:-63.31^-33.75,P<0.000 01)、缩短住院时间(MD=-0.96,95%CI:-1.87^-0.05,P=0.04)、减少手术并发症(OR=0.46,95%CI:0.22~0.97,P=0.04)、提高术后控尿能力(OR=2.39,95%CI:1.48~3.85,P=0.000 3)。结论:与2D腹腔镜比较,3D腹腔镜下经腹膜外前列腺癌根治术能够缩短手术时间、减少术中出血、缩短住院时间、减少术后并发症及提高术后控尿,但由于纳入文献较少且质量不高,需要更多高质量的随机对照研究以进一步证实该结论。Objective：To compare efficacy and safety between 3D and 2D extraperitoneal laparoscopic technique used in radical prostatectomy.Method：We searched several databases to identify related studies.Two independent boffins were employed to carry out the quality evaluation and data extraction of the studies.Revman 5.3 software was used to process statistical analysis.Result：Finally,9 studies were included with 705 cases.Statistical analysis showed that operative time was shortened（MD=-34.74,95%CI：-49.01--20.46,P〈0.000 01）,intraoperative blood loss was reduced（MD=-48.53,95%CI：-63.31--33.75,P〈0.000 01）,hospital stay was reduced（MD=-0.96,95%CI：-1.87--0.05,P=0.04）,surgical complications were reduced（OR=0.46,95%CI：0.22-0.97,P=0.04）,urinary continence was improved（OR=2.39,95%CI：1.48-3.85,P=0.000 3）in 3D extraperitoneal laparoscopic surgery compared with control group.Conclusion：Compared with 2D procedure,3D extraperitoneal laparoscopic assisted radical prostatectomy has advantages in terms of operation duration,blood loss,hospital stay,complications and urinary continence.However,more high-quality randomized controlled trials with large samples are required to provide further support to our findings.

关 键 词：三维 腹腔镜 前列腺癌根治术 前列腺肿瘤 META分析 

分 类 号：R737.25[医药卫生—肿瘤]