加速康复外科对Ⅱ～Ⅲ期结直肠癌患者术后长期生存的影响  

The effect of enhanced recovery after surgery on postoperative long-term survival in patients of stage Ⅱ-Ⅲ colorectal cancer

作　　者：陈诚[1] 唐成武[1] CHEN Cheng;TANG Chengwu(Department of Surgery,the First People＇s Hospital of Huzhou City in Zhejiang Province,Huzhou 313000,China)

机构地区：[1]浙江省湖州市第一人民医院外科,浙江湖州313000

出　　处：《中国现代医生》2018年第23期42-45,共4页China Modern Doctor

基　　金：浙江省自然科学基金资助项目(LY16H160041)

摘　　要：目的探讨加速康复外科措施对Ⅱ~Ⅲ期结直肠癌患者术后长期生存的影响。方法 2012年5月～2014年11月间78例Ⅱ~Ⅲ期结直肠癌患者在本院接受根治手术,其中38例患者接受加速康复外科治疗(ERAS组),其余40例患者接受常规治疗(对照组)。比较两组患者术后长期生存。结果在术后3年内,对照组有16例复发,ERAS组有9例复发,ERAS组3年无瘤生存率明显优于对照组(P=0.0495)。在术后3年内,对照组有15例死亡,ERAS组有8例死亡,ERAS组3年总生存率明显优于对照组(P=0.0498)。结论加速康复外科措施能显著改善Ⅱ~Ⅲ期结直肠癌患者术后长期生存。Objective To investigate the effects of enhanced recovery after surgeryon the postoperative long-term sur- vival of patients with stage Ⅱ-Ⅲ colorectal cancer. Methods From May 2012 to November 2014,78 patients with stage Ⅱ-Ⅲ colorectal cancer underwent radical operation in our hospital. Among them, 38 patients received enhanced recovery after surgery（ERAS group） and the remaining 40 patients received conventional therapy（control group）. Long- term survival was compared between the two groups. Results Within 3 years after operation, 16 cases relapsed in the control group and 9 cases relapsed in the ERAS group. The 3-year disease-free survival rate of the ERAS group was significantly better than that of the control group（P=0.0495）. Within 3 years after operation, 15 patients died in the control group and 8 patients died in the ERAS group. The 3-year overall survival rate in the ERAS group was signifi- cantly better than that in the control group （P=0.0498）. Conclusion Enhanced recovery after surgery can significantly improve long-term postoperative survival in patients with stage Ⅱ-Ⅲ colorectal cancer.

关 键 词：结直肠癌 加速康复外科 总生存期 无瘤生存期 预后 

分 类 号：R735.34[医药卫生—肿瘤]