疏肝理气和胃降逆法治疗胆汁反流性胃炎临床研究  

Clinical Study of Applying Shugan Liqi and Hewei Jiangni Method in the Treatment Ofbile Reflux Gastritis

作　　者：牟琴 周裕婷 彭琼 MOU Qin;ZHOU Yuting;PENG Qiong(Department of Traditional Chinese Medicine,Ba＇nan Hospital of Traditional Chinese Medi-cine（Chongqing 401320,China)

机构地区：[1]重庆市巴南中医院中医科,重庆401320

出　　处：《四川中医》2018年第8期75-77,共3页Journal of Sichuan of Traditional Chinese Medicine

摘　　要：目的:观察疏肝理气、和胃降逆法治疗胆汁反流性胃炎的临床疗效。方法:筛选我院2015年12月~2016年12月收治的106例胆汁反流性胃炎者,随机分为观察组(n=53)与对照组(n=53),对照组给予常规西药治疗,观察组给予疏肝理气、和胃降逆法治疗,持续治疗3个月,比较两组腹痛腹胀、恶心呕吐、暖气反酸、食欲不振等主要症状的中医症候积分改善情况及疾病疗效、胆汁反流疗效及胃黏膜病理组织学疗效的总有效率,并记录两组治疗过程中不良反应发生情况及随访1年的复发率。结果:观察组治疗后腹痛腹胀、恶心呕吐、暖气反酸、食欲不振的中医症候积分均显著低于对照组,差异有统计学意义(P<0.05);观察组疾病疗效、胆汁反流疗效及胃黏膜病理组织学疗效总有效率均显著高于对照组(90.57%vs 73.58%,96.24%vs 83.02%,94.34%vs 79.25%),差异有统计学意义(P<0.05);两组均未出现明显不良反应,观察组1年内复发率3.77%显著低于对照组16.98%,差异有统计学意义(P<0.05)。结论:疏肝理气、和胃降逆法治疗胆汁反流性胃炎标本兼治,疗效显著,可明显改善患者临床症状,抑制胆汁反流,改善患者胃黏膜损伤,降低复发率,具有较高临床应用价值。Objective：To explore the clinical efficacy of Shugan Liqi（Soothing-liver regulating-Qi） and Hewei Jiangni method（harmonizing-stomach and lowering adverse Qi） in the treatment of bile reflux gastritis.Methods：106 cases of patients with bile reflux gastritis admitted to our hospital from December 2015 to December 2016 were selected and randomly divided into observation group（n=53） and controlled group（n=53）.The controlled group was given conventional western medicine,and the observation group was given Shugan Liqi and Hewei Jiangni method,and they were continuously treated for 3 months.The TCM symptoms scores improvement of abdominal pain and distension,nausea and vomiting,heating acid reflux and loss of appetite and other main symptoms,and the total effective rate of efficacy of disease,bile reflux and gastric mucosal histopathology were compared between the two groups,and the occurrence of adverse reactions during treatment and the recurrence rate at 1-year followup were recorded in the two groups.Results：The TCM symptoms scores of abdominal pain and distension,nausea and vomiting,heating acid reflux and loss of appetite in the observation group were significantly lower than those in the controlled group（P〈0.05）.The total effective rates of efficacy of disease,bile reflux and gastric mucosal histopathology in the observation group were significantly higher than those in the controlled group（90.57% vs.73.58%,96.24% vs.83.02%,94.34% vs.79.25%）（P〈0.05）.There was no obvious adverse reactions in the two groups,and the recurrence rate within 1 year in the observation group was significantly lower than that in the controlled group（3.77% vs.16.98%）（P〈0.05）.Conclusions：Shugan Liqi and Hewei Jiangni method for the treatment of bile reflux gastritis can treat the symptoms and the causes with significant efficacy,and it can significantly improve the clinical symptoms,inhibit bile reflux,and enhance gastric mucosal injury and reduce the recurrence rate,and it has high clinical

关 键 词：疏肝理气 和胃降逆 胆汁反流性胃炎 临床疗效 

分 类 号：R573.3[医药卫生—消化系统]