老年缺血性脑血管疾病介入血管支架成型术与药物保守治疗短长期疗效及可能产生并发症对比  

Comparison of Short-Term,Long-Term Efficacy andPossible Complications in Elderly Ischemic Cerebrovascular Diseases with Interventional Vascular Stenting and Drug Conservative Treatment

作　　者：奚宁宁 Xi Ningning(Heilongjiang Rehabilitation Hospital,Ha Erbin,Heilongjiang,150086,China)

机构地区：[1]黑龙江省康复医院,黑龙江哈尔滨150086

出　　处：《当代医学》2018年第26期111-115,共5页Contemporary Medicine

摘　　要：目的探讨老年缺血性脑血管疾病介入血管支架成型术与药物保守治疗短期、长期疗效及可能产生并发症差异。方法选取2015年4月~2017年1月本院收治的107例缺血性脑血管老年患者作为研究对象,根据患者治疗方案不同分为A组(介入血管支架成型术,38例)和B组(药物保守治疗,69例),比较两组患者治疗3、12个月病变血管血流值、神经功能缺损情况、脑血管不良事件发生率及介入手术治疗并发症发生率。结果治疗前,两组患者各病变血管收缩期峰值流速(Vs)比较差异无统计学意义;治疗3个月、治疗12个月A组各病变血管Vs均低于B组,且低于A组治疗前,差异有统计学意义(P<0.05);B组治疗前、治疗3个月及治疗12个月各病变血管Vs比较差异无统计学意义。治疗前,两组患者NIHSS评分比较差异无统计学意义;治疗3个月、治疗12个月A组NIHSS评分均低于B组,且A组治疗12个月NIHSS评分显著低于治疗3个月,差异有统计学意义(P<0.05);B组治疗前、治疗3个月、治疗12个月NIHSS评分比较差异无统计学意义。治疗和随访12个月,A组脑血管不良事件发生率显著低于B组,差异有统计学意义(P<0.05)。A组患者中围手术期共发生4例(12.12%)相关并发症。结论介入血管支架成型术在老年缺血性脑血管疾病中治疗,相对保守药物治疗具有更显著短期、长期疗效,且治疗安全性较高。Objective To investigate the short-term and long-term effects of interventional stenting and conservative treatment for elderly patients with ischemic cerebrovascular disease, and the possible complications. Methods Select 107 case of ischemic cerebrovascular elderly patients in our hospital during April,2015 to January,2017 as studying object, divided into group A （interventional vascular stenting, 38 cases） and group B （pharmaceutical conservative treatment, 69 cases） according to the patient＇s treatment protocol. The blood vessel blood flow and neurological deficits were compared between the two groups of patients treated for 3 months and 12 months. The incidence of cerebrovascular adverse events and the incidence of complications after interventional surgery. Results Before treatment, there was no statistically significant difference in peak systolic velocity（ Vs） between the two groups. In the 3 months of treatment and 12 months of treatment, the Vs of all lesions in group A was lower than that in group B, and was lower than that of group A before treatment, the difference was statistically significant （P〈0.05）. There was no significant change in Vs of all lesions before treatment, 3 months of treatment and 12 months of treatment in group B, comparative differences were not statistically significant. Before the treatment, the NIHSS scores of the two groups were not statistically significant. The NIHSS scores of the two groups were lower than those of the group B in the three months of treatment and December of treatment, and the NIHSS scores of the group A were significantly lower than those of the treatment three months in December, the difference was statistically significant （P〈0.05）; There was no significant change in NIHSS scores before, during and after treatment in group B, comparative differences were not statistically significant. After treatment and follow-up for 12 months, the incidence of cerebral vascular adverse events in group A was significantly lower than that in gr

关 键 词：老年 缺血性脑血管病 介入 支架成型术 药物 疗效 

分 类 号：R743.3[医药卫生—神经病学与精神病学]