营养支持联合睡眠干预对消化道恶性肿瘤患者生命质量的影响  

Effect of Nutritional Support Combined with Sleep Intervention on Quality of Life in Patients with Digestive Tract Cancer

作　　者：齐淑静[1] 齐瑞霞 张午临 孙宇航[1] 康艳辉[3] 付泽娴[1] 杨福申[1] 霍忠超[1] 于晓娟[1] 张宝霞[1] 任勇[1] Qi Shujing;Qi Ruixia;Zhang Wulin;Sun Yuhang;Kang Yanhui;Fu Zexian;Yang Fushen;Huo Zhongchao;Yu Xiaojuan;Zhang Baoxia;Ren Yong(affiliated Hospital of Hebei University of Engineering,Handan,056002;Handan City Central Hospital,Handan,056000;Handan University of Engineering Medical College,Handan,056002)

机构地区：[1]河北工程大学附属医院,邯郸056002 [2]邯郸市中心医院,邯郸056000 [3]河北工程大学医学院,邯郸056002

出　　处：《世界睡眠医学杂志》2018年第6期635-638,共4页World Journal of Sleep Medicine

基　　金：邯郸市科技局计划内项目(1623208061-3)

摘　　要：目的:探讨营养支持联合睡眠干预对消化道恶性肿瘤患者生命质量的影响。方法:选取2016年11月至2018年1月河北工程大学附属医院收治的消化道恶性肿瘤患者183例,按随机数表法将其分为观察组和对照组。其中,观察组给予营养支持联合睡眠干预治疗方法;对照组患者给予常规干预治疗方法。观察2组患者手术后的肝功能指标、白蛋白、前白蛋白、总蛋白、血红蛋白、住院时间、胃肠道恢复时间、排气情况及生命质量指标。结果:2组患者经过干预后,观察组肝功能指标比较于对照组明显改善,差异有统计学意义(P<0.05)。2组患者经过干预后,观察组的白蛋白(33.9±1.8)g/L、前白蛋白(28.6±1.8)g/L、总蛋白(64.3±3.1)g/L、血红蛋白(107.3±7.1)g/L较对照组(31.2±1.6 g/L、26.9±5.2 g/L、60.6±1.4 g/L、103.6±7.4 g/L)明显改善,差异有统计学意义(P<0.05)。2组患者经过干预后,观察组在住院时间(7.3±2.3)d、胃肠道恢复时间(14.5±3.1)d及排气时间(45.8±5.6)h方面均少于对照组(11.6±3.3 d、21.4±4.3 d、75.5±6.5 h),差异有统计学意义(P<0.05)。观察组在生理功能(75.1±8.2)、生理职能(65.5±9.7)、精神健康(67.6±10.3)、总体健康(67.4±8.5)、活力(60.6±10.2)方面得分均大于对照组(70.2±7.3、53.6±7.8、61.3±8.3、66.4±9.1、53.7±8.3),差异有统计学意义(P<0.05)。结论:营养支持联合睡眠干预治疗的方法能够明显改善消化道恶性肿瘤患者手术后的肝功能指标、白蛋白、前白蛋白、总蛋白、血红蛋白、住院时间、胃肠道恢复时间、排气情况和生命质量,具有一定的临床参考价值。Objective： To investigate the effect of nutritional support combined with sleep intervention on the quality of life of patients with gastrointestinal cancer. Methods： A total of 183 patients with gastrointestinal malignancies admitted to our hospital from November 2016 to January 2018 were selected and divided into observation group and control group according to the random number table method. Among them,the observation group was given nutritional support combined with sleep intervention treatment; the control group patients were given conventional intervention treatment. Observe the indicators of liver function,albumin,prealbumin,total protein,hemoglobin,length of hospital stay,gastrointestinal recovery time,exhalation,and quality of life indicators after surgery in both groups. Results： After intervention in the two groups,the observation group liver function index Compared with the control group,the difference was statistically significant Significance（P〈0. 05）. After intervention in the two groups,the observation group albumin（33. 9 ± 1. 8） g/L,prealbumin（28. 6 ± 1. 8） g/L,total protein（64. 3 ± 3. 1） g/L,hemoglobin（107. 3 ± 7. 1） g/L ratio was significantly improved compared with the control group（31. 2 ± 1. 6 g/L,26. 9 ± 5. 2 g/L,60. 6 ± 1. 4 g/L,103. 6 ± 7. 4 g/L）（P〈0. 05）. After intervention in the two groups,the observation group was less than the control group at the hospitalization time（7. 3 ± 2. 3） d,gastrointestinal recovery time（14. 5 ± 3. 1） d,and venting time（45. 8 ± 5. 6） h（11. 6 ± 3. 3）d,（21. 4 ± 4. 3） d,（75. 5 ± 6. 5） h,the difference was statistically significant（P〈0. 05）. In the observation group,the scores of physiological function（75. 1 ± 8. 2）,physiological function（65. 5 ± 9. 7）,mental health（67. 6 ±10. 3）,general health（67. 4 ± 8. 5） and vitality（60. 6 ± 10. 2） were all greater than those of the control group（70. 2± 7. 3,53. 6 ± 7. 8,61. 3 ± 8. 3,66. 4 ± 9. 1,53. 7 ± 8. 3）,

关 键 词：营养支持 睡眠干预 消化道恶性肿瘤 生命质量 

分 类 号：R735[医药卫生—肿瘤]