微创血管内介入栓塞术治疗颅脑动脉瘤临床研究  

Clinical study on minimally invasive endovascular interventional embolization in the treatment of craniocerebral aneurysms

作　　者：黄春波[1] 杨瑞生[1] 黄亚楠 李庆安[1] 王伟丰[1] 靳晓亮[1] HUANG Chunbo;YANG Ruisheng;HUANG Yanan;LI Qing＇an;WANG Weifeng;J IN Xiaoliang(）Department of Neurosurgery,the People＇s Hospital of Jiyuan,Jiyuan 459000,China;）Department of Orthopedics,the People＇s Hospital of Jiyuan,Jiyuan 459000,China)

机构地区：[1]济源市人民医院神经外科,河南济源459000 [2]济源市人民医院骨科,河南济源459000

出　　处：《中国实用神经疾病杂志》2018年第18期2054-2062,共9页Chinese Journal of Practical Nervous Diseases

摘　　要：目的探讨微创血管内介入栓塞术对颅脑动脉瘤患者术后脑组织血流量及生存质量的影响。方法选取济源市人民医院81例颅脑动脉瘤患者,根据手术术式不同分为对照组40例,观察组41例,对照组予以开颅夹闭术治疗,观察组予以微创血管内介入栓塞术治疗,观察2组手术前后脑组织血流量(CBF)变化情况、并发症发生情况及手术前后生存质量评分。结果阻断颅内动脉瘤时及术后观察组CBF均低于对照组,且2组阻断颅内动脉瘤时、术后CBF均较术前有所变化,但观察组变化幅度小于对照组,差异具有统计学意义(P<0.05);观察组并发症发生率为4.88%(2/41),低于对照组22.50%(9/40),差异具有统计学意义(P<0.05);术后观察组生存质量各指标评分均高于对照组,差异具有统计学意义(P<0.05)。结论微创血管内介入栓塞术对颅脑动脉瘤患者术后脑组织血流量影响小,可提高患者生存质量,降低并发症发生率。Objective To investigate the effect of minimally invasive endovascular interventional embolization on postopera tive cerebral blood flow and quality of life in patients withcraniocerebralaneurysms. Methods Atotalof81 cases of craniocerebral aneurysm in our hospital were divided into the control group of 40 cases and the observation group of 41 cases. The control group was treated with craniotomy,and the observation group was treated with minimally invasive endovascular interventional emboliza tion. The changes of cerebral blood flow （CBF） before and after operation,the occurrence of complications and the quality of life before and after operation were compared between the two groups. Results At the time when the intracranial aneurysms were blocked and after operation,the CBF in the observation group were lower than that in the control group. And at the time when the intracranial aneurysms were blocked and after operation,the CBF in two group changed compared with that before operation, but the change range of the observation group was smaller than that of the control group, and the difference was statistically significant （P〈0. 05）. The incidence of complications in the observation group was 4.88% （2/41） ,which was lower than that of the control group （22.50% （9/40）） ,and the difference was statistically significant（P〈0.05）. The score of the quality of life of the observa tion group was higher than that of the control group after the operation, and the difference was statistically significant（P〈0.05）. Conclusion Minimally invasive endovascular interventional embolization has little effect on cerebral blood flow in patients with craniocerebral aneurysms after operation. It can improve the patient＇s quality of life and reduce the incidence of complications.

关 键 词：微创血管内介入栓塞术 颅脑动脉瘤 脑组织血流量 生存质量 并发症 

分 类 号：R739.4[医药卫生—肿瘤]